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. Author manuscript; available in PMC: 2016 Sep 15.
Published in final edited form as: Acta Biomater. 2015 Jun 15;24:309–321. doi: 10.1016/j.actbio.2015.06.012

Figure 3.

Figure 3

SEM images and roughness analysis of the 2.45-inf-RAP particles measured ex-situ during the course of an in vitro drug release experiment (HBSS, 37 °C). Ra: Arithmetical mean deviation of the roughness profile; Rsk: Skewness of the roughness profile; Rku: Kurtosis of the roughness profile. The 21-day image demonstrated obvious pSi erosion compared with 0-day samples. Due to the unevenness erosion, Ra did not well capture the profile change; but both Rsk and Rku showed elevation, indicating presence of high spikes and deep valleys on the 21-day sample.