Table 6.

Comparison of mean improvement in quality of life scores for CRS patients with and without comorbid anxiety

	CRS with comorbid anxiety (n=20)		CRS without comorbid anxiety (n=92)
Quality of life measures:	Mean [SD]	Relative Change	Mean [SD]	Relative Change	p-value
SNOT-22 total score	−18.1[19.5] **	31%	−29.0[21.0] *	52%	0.03
Rhinologic symptoms	−5.4[6.4] **	34%	−9.0[6.3] *	53%	0.02
Extra-nasal rhinologic symptoms	−2.4[4.0] **	31%	−4.3[3.7] *	52%	0.08
Ear and/or facial symptoms	−4.3[3.9] *	42%	−5.5[5.0] *	56%	0.28
Psychological dysfunction	−5.2[8.4] **	27%	−8.3[8.5] *	49%	0.19
Sleep dysfunction	−4.2[7.1] **	28%	−7.7[7.1] *	49%	0.04
RSDI total scores	−17.3[29.3] **	32%	−26.5[22.4] *	57%	0.12
Physical subdomain	−6.9[9.8] **	34%	−11.7[9.1] *	61%	0.05
Functional subdomain	−6.1[10.2] **	36%	−8.8[8.4] *	59%	0.29
Emotional subdomain	−4.3[12.0]	25%	−5.9[7.6] *	48%	0.59

^*indicates significant postoperative improvement over time (p<0.001)

^**indicates significant postoperative improvement over time (p<0.050).

Negative mean scores indicate improvement over time. SD, standard deviation; SNOT-22, 22-item Sinonasal Outcome Test; RSDI, Rhinosinusitis Disability Index.