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. Author manuscript; available in PMC: 2016 Sep 10.
Published in final edited form as: Exp Cell Res. 2015 Jul 21;337(1):120–127. doi: 10.1016/j.yexcr.2015.07.017

Figure 4.

Figure 4

NF-κB signaling pathway was not required for SOCS3-enhanced generation of proinflammatory mediators in IgG IC-treated macrophages. A, indicated plasmids were transduced into RAW-Neo cells, and RAW-SOCS3 cells, respectively. 48 h later, the cells were treated with or without 100 μg/ml IgG IC for 4 h. Then cells were lysed and subjected to luciferase assays. Data were expressed as means ± S. E. M. (n=3, biological replicates). B, RAW-Neo and RAW-SOCS3 defective peritoneal macrophages were treated with or without 100 μg/ml IgG IC. 4 h later, nuclear proteins were extracted and subjected to gel shift assay.