Table 3.
Standardised incidence ratios of colorectal cancer in individuals diagnosed with colorectal adenomas.
| Group | No. cases | No. CRC expected | No. CRC observed | SIR (95% CI) |
|---|---|---|---|---|
| Adenomas a | ||||
| All | 6,972 | 68 | 193 | 2.85 (2.61–3.25) |
| Female | 3,157 | 25 | 68 | 2.69 (2.30–3.33) |
| Male | 3,815 | 45 | 125 | 2.76 (2.47–3.25) |
| Advanced adenomas b | 3,819 | 38 | 105 | 1.75 (2.43–3.28) |
| All, excluding CRC in 1st year of follow-up | 6,834 | 68 | 157 | 2.32 (2.10–2.69) |
|
| ||||
| Hyperplastic polyps | ||||
| All | 3,464 | 23 | 41 | 1.79 (1.34–2.14) |
| Female | 1,668 | 9 | 17 | 1.89 (1.34–2.78) |
| Male | 1,796 | 14 | 24 | 1.67 (1.26–2.34) |
| No subsequent adenoma | 3,382 | 22 | 40 | 1.80 (1.46–2.36) |
CRC: Colorectal cancer. SIR: Standardised Incidence Ratios.
a
Incorporates n=858 individuals diagnosed with concurrent hyperplastic polyps as outlined in Figure 1.
b
Individuals with multiple adenomas or ≥1 villous/tubulovillous adenomas were classified as advanced. The polyp register did not contain detailed information on polyp size.