Table 2.

Mean differences in subclinical CVD measures at baseline and mean differences in annual change associated with occupational category at baseline by sex

	Common carotid IMT				Carotid plaque score				Prevalence of carotid plaque shadowing
	Model 1		Model 2		Model 1		Model 2		Model 1		Model 2
	Mean difference, mm	(95% CI)	Mean difference, mm	(95% CI)	Difference, %	(95% CI)	Difference, %	(95% CI)	Difference, %	(95% CI)	Difference, %	(95% CI)
Men
Difference at baseline
Management	−0.005	(−0.031 to 0.022)	−0.005	(−0.032 to 0.021)	48.6	(22.6 to 80.2)	43.7	(18.9 to 73.8)	35.2	(1.4 to 80.2)	34.1	(0.1 to 79.6)
Professional (ref.)	0.000		0.000		0.0		0.0		0.0		0.0
Sales/office	0.012	(−0.019 to 0.043)	0.007	(−0.025 to 0.040)	46.6	(17.3 to 83.1)	36.1	(9.3 to 69.5)	34.0	(−3.4 to 85.8)	26.0	(−10.3 to 77.0)
Service	0.005	(−0.029 to 0.040)	0.002	(−0.036 to 0.040)	35.7	(4.8 to 75.8)	28.3	(−1.0 to 66.3)	34.4	(−8.3 to 97.0)	29.8	(−13.9 to 95.7)
Blue-collar	0.000	(−0.027 to 0.027)	−0.006	(−0.037 to 0.025)	50.1	(23.5 to 82.4)	40.6	(15.5 to 71.1)	26.1	(−5.3 to 67.9)	23.7	(−9.2 to 68.5)
	p=0.891		p=0.919		p=0.001		p=0.001		p=0.242		p=0.361
Difference in annual change
Management	0.001	(−0.001 to 0.003)	0.001	(−0.001 to 0.003)	−1.7	(−3.4 to -0.1)	−1.6	(−3.3 to 0.1)	−1.9	(−5.6 to 1.9)	−1.9	(−5.6 to 2.0)
Professional (ref.)	0.000		0.000		0.0		0.0		0.0		0.0
Sales/office	0.002	(−0.001 to 0.004)	0.001	(−0.002 to 0.004)	−0.4	(−2.3 to 1.5)	−0.3	(−2.3 to 1.6)	−1.9	(−6.1 to 2.5)	−1.8	(−6.0 to 2.7)
Service	0.002	(−0.001 to 0.005)	0.002	(−0.001 to 0.004)	0.2	(−2.2 to 2.5)	0.2	(−2.1 to 2.6)	−1.8	(−6.7 to 3.3)	−1.3	(−6.3 to 4.1)
Blue-collar	0.001	(−0.001 to 0.003)	0.000	(−0.002 to 0.003)	−1.0	(−2.7 to 0.6)	−1.1	(−2.8 to 0.5)	−0.4	(−4.1 to 3.4)	−0.5	(−4.2 to 3.4)
	p=0.589		p=0.784		p=0.242		p=0.238		p=0.820		p=0.857
Women
Difference at baseline
Management	0.006	(−0.019 to 0.030)	0.005	(−0.020 to 0.029)	1.5	(−19.8 to 28.6)	−7.1	(−26.3 to 17.1)	13.0	(−20.7 to 61.1)	5.2	(−26.8 to 51.0)
Professional (ref.)	0.000		0.000		0.0		0.0		0.0		0.0
Sales/office	0.008	(−0.012 to 0.028)	0.001	(−0.021 to 0.023)	21.2	(0.9 to 45.5)	7.2	(−10.6 to 28.5)	14.8	(−12.9 to 51.2)	2.0	(−24.0 to 36.8)
Service	0.006	(−0.019 to 0.030)	−0.008	(−0.034 to 0.019)	16.7	(−6.6 to 46.0)	1.4	(−18.7 to 26.6)	4.3	(−25.8 to 46.6)	−9.7	(−37.4 to 30.3)
Blue-collar	0.017	(−0.012 to 0.046)	0.005	(−0.026 to 0.035)	13.3	(−12.6 to 46.9)	−0.4	(−22.7 to 28.3)	2.6	(−29.8 to 49.8)	−12.6	(−41.7 to 31.2)
	p=0.825		p=0.911		p=0.267		p=0.806		p=0.878		p=0.896
Difference in annual change
Management	0.001	(−0.001 to 0.003)	0.001	(−0.001 to 0.003)	0.5	(−1.7 to 2.8)	0.8	(−1.5 to 3.2)	−1.9	(−6.4 to 2.8)	−1.8	(−6.4 to 3.0)
Professional (ref.)	0.000		0.000		0.0		0.0		0.0		0.0
Sales/office	0.000	(−0.002 to 0.002)	0.000	(−0.002 to 0.002)	−0.3	(−1.9 to 1.4)	−0.5	(−2.2 to 1.2)	0.6	(−2.9 to 4.3)	0.1	(−3.4 to 3.8)
Service	−0.002	(−0.004 to 0.000)	−0.002	(−0.004 to 0.000)	−0.2	(−2.1 to 1.9)	0.0	(−2.0 to 2.1)	0.4	(−3.8 to 4.8)	0.4	(−3.9 to 4.9)
Blue-collar	0.000	(−0.003 to 0.002)	−0.001	(−0.003 to 0.002)	0.4	(−1.9 to 2.8)	0.3	(−2.0 to 2.7)	1.9	(−2.9 to 6.9)	2.0	(−2.9 to 7.1)
	p=0.213		p=0.281		p=0.957		p=0.813		p=0.746		p=0.793

Model 1 is adjusted for age, race/ethnicity, nativity, family history of heart attack, employment status at each data collection, time since baseline, field centre and the interaction of age and time. In addition Model 2 includes education, household income, smoking status, pack-years for ever smokers, body mass index, systolic and diastolic blood pressure, total/HDL cholesterol ratio, diabetes, dyslipidemia medication and hypertension medication. For the IMT models, the left and right carotid arteries are also accounted for.

CVD, cardiovascular disease; HDL, high-density lipoprotein; IMT, intima-media thickness.