Table 2.

Incidence rates and HRs for Alzheimer’s disease according to the presence of gout

	Gout (n=59 224)	No gout (n=238 805)
Cases, n	309	1942
Follow-up time, person-years	299 799	1 258 059
Mean follow-up, years	5.1	5.3
Incidence rate (cases per 1000 person-years)	1.0 (0.9 to 1.2)	1.5 (1.4 to 1.6)
Age-matched, sex-matched, entry-time-matched, BMI-matched HR (95% CI)	0.71 (0.62 to 0.80)	1.0 (reference)
+Continuous BMI-adjusted HR (95% CI)	0.71 (0.62 to 0.80)	1.0 (reference)
+Diuretics-adjusted HR (95% CI)	0.76 (0.68 to 0.87)	1.0 (reference)
+Other CV drugs (95% CI)	0.76 (0.67 to 0.87)	1.0 (reference)
+CV comorbidities (95% CI)	0.76 (0.67 to 0.88)	1.0 (reference)
+GPs visits, smoking, alcohol and SDI (95% CI)	0.76 (0.66 to 0.87)	1.0 (reference)

BMI, body mass index; CV, cardiovascular; GP, general practitioner; SDI, social–economic deprivation index.