Table 2.
Key Grade 3–5 Adverse Event Incidence, Any Attribution
| A (n=42) | B (n=44) | C (n=48) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Grade | Grade | Grade | |||||||
| 3 | 4 | 5 | 3 | 4 | 5 | 3 | 4 | 5 | |
| Adverse Event Type | (n) | (n) | (n) | (n) | (n) | (n) | (n) | (n) | (n) |
| Anemia | 7 | 0 | 0 | 3 | 1 | 0 | 5 | 1 | 0 |
| Febrile neutropenia | 3 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 |
| Fatigue | 6 | 0 | 0 | 9 | 0 | 0 | 5 | 0 | 0 |
| Rash acneiform | 2 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 |
| Diarrhea | 0 | 0 | 0 | 1 | 0 | 0 | 4 | 0 | 0 |
| Nausea | 5 | 0 | 0 | 3 | 0 | 0 | 4 | 0 | 0 |
| Vomiting | 3 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 0 |
| Lung Infection | 3 | 0 | 1 | 2 | 0 | 0 | 3 | 0 | 0 |
| Neutrophil count decreased | 3 | 9 | 0 | 5 | 8 | 0 | 6 | 14 | 0 |
| Platelet count decreased | 1 | 2 | 0 | 1 | 5 | 0 | 2 | 4 | 0 |
| Anorexia | 3 | 0 | 0 | 4 | 0 | 0 | 2 | 0 | 0 |
| Dehydration | 1 | 0 | 0 | 2 | 0 | 0 | 3 | 0 | 0 |
| Hyperglycemia | 1 | 0 | 0 | 6 | 0 | 0 | 5 | 3 | 0 |
| Hyponatremia | 1 | 0 | 0 | 2 | 0 | 0 | 8 | 0 | 0 |
| Arthralgia | 3 | 0 | 0 | 4 | 0 | 0 | 3 | 0 | 0 |
| Myalgia | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 |
| Dyspnea | 10 | 1 | 0 | 6 | 0 | 0 | 4 | 2 | 0 |
| Thromboembolic event | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 0 | 0 |