Table 2.
Baseline characteristics of the study population to date
| Variable | Full Cohort (N = 217) | SPPB ≥ 10 (N = 95) | SPPB < 10 (N = 122) |
|---|---|---|---|
| Age (years) | 70.3 (60–79.1) | 62.9 (52.9–72.3) | 74.6 (63.4–82.5) |
| Gender (Female) | 84 (40.0 %) | 27 (29.4 %) | 57 (48.3 %) |
| Weight (kg) | 83 (71.7–96.6) | 81.2 (72–95.9) | 86.1 (71.7–96.6) |
| Systolic Blood Pressure (mmHg) | 137 (124–151) | 135 (123–149) | 140 (126–151) |
| Diastolic Blood Pressure (mmHg) | 74 (66–82) | 78 (68–85) | 71 (65–78) |
| Pulse Pressure (mmHg) | 64 (52–76) | 59 (48–70) | 69.5 (57–79) |
| Laboratory Values | |||
| eGFR (mL/min/1.73 m2) | 19 (14–27) | 18 (13–26) | 20 (16–27) |
| Creatinine (umol/L) | 250.5 (189–334) | 273.5 (202–404) | 229 (186–309) |
| Log Urine ACR | 3.3 (1–5.1) | 3.3 (1.1–5) | 3.3 (0.9–5.2) |
| Hemoglobin (g/L) | 114 (107–124.5) | 118 (110–126) | 113 (105–122) |
| Hemoglobin A1c (%) | 6.3 (5.7–7.9) | 5.9 (5.5–7.5) | 6.8 (5.8–8.1) |
| Blood Glucose (mmol/L) | 6.6 (5.4–9.6) | 6.2 (5.3–8.5) | 7.3 (5.5–9.9) |
| Comorbidities | |||
| Visual or Hearing Impairment | 101 (46.5 %) | 32 (33.7 %) | 69 (56.6 %) |
| Hypertension | 181 (85.0 %) | 76 (80.0 %) | 105 (89.0 %) |
| Dyslipidemia | 133 (63.0 %) | 55 (57.9 %) | 78 (67.2 %) |
| Diabetes (Type I or II) | 128 (60.4 %) | 40 (42.1 %) | 88 (75.2 %) |
| Previous MI | 29 (13.7 %) | 8 (8.4 %) | 24 (20.5 %) |
| Congestive Heart Failure | 31 (14.6 %) | 5 (5.3 %) | 24 (20.5 %) |
| Neurologic Disease | 51 (24.1 %) | 3 (3.2 %) | 9 (7.7 %) |
Note: Continuous variables are expressed as Median (Interquartile Range) and compared using Mann–Whitney Test; Categorical variables are expressed as N(%) and compared using Chi-Square or Fisher Exact Test
Neurologic Disease contains stroke, transient ischemic attack and Parkinson’s disease. ACR Albumin Creatinine Ratio, MI Myocardial Infarction