Table 3.

DHEA-related brain activation associated with viewing fear vs calm faces

Region	Cluster size	Peak Z	Peak MNI coordinates
			x	y	z
Negative association with DHEA (whole sample)
Right posterior insula	179	3.3	42	−12	−3
Right anterior mid-cingulate	248	3.19	4	0	33
Negative association with DHEA (females)
Right posterior insula	2598	4.32	38	−4	3
Right posterior mid-cingulate	760	4.11	6	−10	30
Left posterior insula	3062	3.87	−30	−18	7
Left dorsolateral prefrontal	538	3.32	−45	33	21
Right dorsolateral prefrontal	202	3.27	45	45	9
Left caudate	158	3.24	−18	18	7
Right dorsal anterior cingulate	182	2.92	10	20	34

Note: Clusters of significant activation that survived statistical threshold for multiple comparisons (montecarlo simulation determined cluster size >146 voxels).