Table 5.

DHEA-related brain activation associated with viewing happy vs calm faces

Region	Cluster size	Peak Z	Peak MNI coordinates
			x	y	Z
Negative association with DHEA (whole sample)
Left dorsal cingulate	224	3.39	−3	−1	30
Negative association with DHEA (females)
Right posterior insula	388	3.72	44	−6	−8
Right mid insula	217	3.63	32	4	19
Right posterior cingulate	1017	3.57	8	−13	33
Left anterior insula	679	3.31	−28	21	1
Positive association with DHEA (females)
Left subgenual cingulate	214	4.34	−8	12	−21
Right ventromedial prefrontal	239	3.94	14	27	−20

Note: Clusters of significant activation that survived statistical threshold for multiple comparisons (montecarlo simulation determined cluster size >146 voxels).