. Author manuscript; available in PMC: 2016 Jul 25.

Published in final edited form as: Am J Nephrol. 2015 Jul 25;41(6):438–447. doi: 10.1159/000437342

Table 4.

Threshold analyses for detection of parameters of kidney disease in patients with type 2 diabetes, by race

Diagnostic performance	African American		European American
Diagnostic performance	UACR >300 mg/g	eGFR <60 ml/min/1.73m²	UACR >300 mg/g	eGFR <60 ml/min/1.73m²
Cut-point	32.5	37.6	46.9	44.4
AUC	0.616 (0.556, 0.675)	0.744 (0.701, 0.786)	0.644 (0.57, 0.719)	0.74 (0.682, 0.798)
Sensitivity	0.696 (0.606, 0.774)	0.693 (0.626, 0.753)	0.617 (0.49, 0.729)	0.686 (0.599, 0.762)
Specificity	0.511 (0.463, 0.558)	0.698 (0.647, 0.745)	0.642 (0.575, 0.703)	0.729 (0.654, 0.793)
NPV	0.835 (0.796, 0.878)	0.872 (0.848, 0.897)	0.834 (0.79, 0.883)	0.874 (0.845, 0.906)
PPV	0.322 (0.286, 0.354)	0.434 (0.384, 0.476)	0.364 (0.295, 0.421)	0.458 (0.376, 0.52)

ESC=electrochemical skin conductance; UACR=urine albumin:creatinine ratio; eGFR=estimated glomerular filtration rate; AUC=area under the curve; NPV=negative predicted probability; PPV=positive predicted probability