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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Genet Med. 2015 Mar 5;17(11):912–918. doi: 10.1038/gim.2015.6

Table 1.

Antibody response in HSAT, SIT and LT groups at peak titer and last titer measurements

Group Patient Peak titers Weeks on ERT at
peak titers
Last titers Weeks on ERT at
last titers
HSAT 1 204 800 78 102 400 152
2 204 800 60 102 400 181
3 102 400 24 51 200 36
4 204 800 64 204 800 64
5 409 600 64 409 600 82
6 1 638 400 52 1 638 400 64
7 204 800 38 102 400 52
8 51 200 24 25 600 38
9 409 600 64 409 600 64
10 819 200 86 819 200* 86
11 51 200 28 51 200 63
12 819 200 130 409 600 138
13 819 200 29 819 200 29
Median 204 800 60 204 800 64
Range 51 200 – 1 638 400 24 – 130 25 600 – 1 638 400 29 – 181
SIT 14 51 200 15 6 400 202
15 25 600 16 6 400 90
16 25 600 117 6 400 194
17 25 600 24 12 800 132
Median 25 600 20 6 400 145
Range 25 600 – 51 200 15 – 117 6 400 – 25 600 90 – 202
LT 18 800 26 100 112
19 200 100 100 110
20 200 48 0 84
Median 200 48 100 110
Range 200 – 800 26 – 100 0 – 100 84 – 112
*

Indicates the last titer value before the initiation of ITI

HSAT, high sustained antibody titers; LT, low titers; SIT, sustained intermediate titers; ITI, immune tolerance induction