Table 5.
Oridonin top interacting genes
Interacting gene | Interaction | References |
---|---|---|
IL10 | Increases expression of the protein | [18] |
IL2 | Increases expression of the protein | [18] |
IFNG | Decreases expression of the protein | [55] |
HMOX1 | Increases mRNA expression | [18] |
HMOX1 | Increases expression of the protein | [18] |
CASP3 | Increases cleavage of the protein | [105] |
BCL2 | Decreases expression of the protein | [106] |
PARP1 | Increases cleavage of the protein | [20] |
TGFB1 | Increases expression of the protein | [107] |
BCL B-cell lymphoma, HMOX heme oxygenase, IFNG interferon gamma, IL interleukin, mRNA messenger RNA, PARP poly (ADP-ribose) polymerase, TGFB transforming growth factor B