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. 2015 Aug 20;15(3):233–244. doi: 10.1007/s40268-015-0102-z

Table 5.

Oridonin top interacting genes

Interacting gene Interaction References
IL10 Increases expression of the protein [18]
IL2 Increases expression of the protein [18]
IFNG Decreases expression of the protein [55]
HMOX1 Increases mRNA expression [18]
HMOX1 Increases expression of the protein [18]
CASP3 Increases cleavage of the protein [105]
BCL2 Decreases expression of the protein [106]
PARP1 Increases cleavage of the protein [20]
TGFB1 Increases expression of the protein [107]

BCL B-cell lymphoma, HMOX heme oxygenase, IFNG interferon gamma, IL interleukin, mRNA messenger RNA, PARP poly (ADP-ribose) polymerase, TGFB transforming growth factor B