Table 1.
The top candidate genes and the number of SNPs among each gene.
| Gene | Chromosome | Number of SNPs | Potential pathways |
|---|---|---|---|
| APOE | 19 | 6 | Cholesterol/lipid metabolism |
| BIN1 | 2 | 101 | Endocytic pathways |
| CLU | 8 | 32 | Immune and cholesterol/lipid metabolism |
| ABCA7 | 19 | 36 | Cholesterol/lipid metabolism; immune and complement systems/inflammatory response |
| CR1 | 1 | 71 | Immune and complement systems/inflammatory response |
| PICALM | 11 | 138 | Endocytic pathways |
| MS4A6A | 11 | 12 | Immune and complement systems/inflammatory response |
| CD33 | 19 | 13 | Immune and complement systems/inflammatory response |
| CD2AP | 6 | 61 | Endocytic pathways; immune and complement systems/inflammatory response |