Table 3.
Regression analysis of risk factors for ACE in Children (<18 years)
| % | % | Unadjusted | Adjusted | |||
|---|---|---|---|---|---|---|
| Risk Factor | Controls | Cases | OR (95% CI) | p-value | OR (95% CI) | p-value |
| Family history of seizure | 14.0(24/172) | 30.8(44/143) | 2.74(1.52,5.02) | 0.0003 | 3.31(1.83,5.96) | <0.001 |
| Maternal seizures | 0.6(1/172) | 1.4(2/144) | 2.41(0.12,142.89) | 0.593 | 2.92(0.26,32.81) | 0.386 |
| Abnormal delivery | 3.7(6/164) | 9.2(13/141) | 2.67(0.91,8.80) | 0.057 | 2.99(1.07,8.34) | 0.036 |
| Abnormal antenatal period | 11.5(19/165) | 17.8(24/135) | 1.66(0.83,3.38) | 0.138 | 1.87(0.94,3.75) | 0.075 |
| Home delivery | 71.3(119/167) | 79.6(113/142) | 1.57(0.90,2.77) | 0.113 | 1.47(0.85,2.55) | 0.173 |
| Problems after birth | 2.4(4/164) | 7.7(11/142) | 3.36(0.96,14.75) | 0.036 | 3.51(1.02,12.06) | 0.047 |
| Difficulties feeding, crying or breathing | 0.6(1/164) | 31.6(43/136) | 75.37(12.27,3062.68) | <0.001 | 73.04(9.81,544.07) | <0.001 |
| Head injury | 18.7(32/171) | 25.0(36/144) | 1.45(0.82,2.57) | 0.216 | 1.45(0.82,2.54) | 0.2 |
| Malnourished | 20.8(32/154) | 12.5(15/120) | 0.54(0.26,1.11) | 0.077 | 0.56(0.28,1.12) | 0.102 |
| Eats cassava | 100.0(170/170) | 96.5(138/143) | 0.00(0.00,0.63) | 0.019 | 1.00(1.00,1.00) | |
| Dogs in household | 48.3(83/172) | 47.6(68/143) | 0.97(0.61,1.55) | 0.91 | 0.93(0.58,1.50) | 0.777 |
| Cats in household | 33.1(57/172) | 34.3(49/143) | 1.05(0.64,1.73) | 0.905 | 0.97(0.59,1.58) | 0.896 |
| Eats Pork | 51.2(88/172) | 53.8(77/143) | 1.11(0.70,1.78) | 0.652 | 1.12(0.70,1.78) | 0.646 |
| Malaria IgG +ve (schizont) | 99.1(116/117) | 100.0(93/93) | NA | 1 | NA | NA |
| Hospitalised with malaria or fever | 0.0(0/173) | 0.0(0/145) | NA | NA | NA | NA |
| Toxocara canis IgG4 +ve | 13.7(16/117) | 14.0(13/93) | 1.03(0.43,2.42) | 1 | 0.97(0.42,2.24) | 0.935 |
| Toxoplasma gondii IgG +ve | 42.7(50/117) | 51.6(48/93) | 1.43(0.80,2.56) | 0.213 | 1.06(0.58,1.94) | 0.852 |
| Taenia solium +ve | 6.9(8/116) | 4.3(4/93) | 0.61(0.13,2.36) | 0.554 | 0.40(0.10,1.66) | 0.207 |
| Onchocerca volvulus +ve | 16.2(19/117) | 33.3(31/93) | 2.58(1.28,5.26) | 0.005 | 2.32(1.12,4.78) | 0.023 |
| HIV +ve | 20.5(24/117) | 25.8(24/93) | 1.35(0.67,2.71) | 0.41 | 1.35(0.67,2.73) | 0.395 |
Odds ration adjusted for: age, sex, maternal education, maternal marital status and employment of either parent. Fisher's exact test for unadjusted p-values.