Skip to main content
. Author manuscript; available in PMC: 2016 Sep 15.
Published in final edited form as: J Immunol. 2015 Aug 12;195(6):2571–2579. doi: 10.4049/jimmunol.1500792

Figure 1. Deletion of MHCII in B cells.

Figure 1

(A) Representative histograms of MHCII staining of splenic B cells from control, MHCIIfl/fl, and CD19-Cre MHCIIfl/fl mice. Cells were first gated as EMA− TCRβ−, then CD19HiCD138−.

(B) Frequency of MHCII+ splenic B cells, as identified as in (A), in the experimental cohorts. Data are pooled from 6 independent cohorts of 12 week old mice; control n=30 and CD19-Cre n=32. Data are represented as mean +/− SEM. Statistics were calculated by two-tailed Mann-Whitney test. ****p < 0.0001.