Table 2.

Five most significantly activated pathways for each comparison of the study.

Group/comparison	3 days	8 days	14 days
No treadmill training  versus control	Protein ubiquitination pathway	Mitochondrial dysfunction	Mitochondrial dysfunction
	Mitochondrial dysfunction	Valine, leucine, and isoleucine degradation	Synthesis and degradation of ketone bodies
	Oxidative phosphorylation	Propanoate metabolism	Oxidative phosphorylation
	Regulation of eIF4 and p70S6K signaling	Butanoate metabolism	Citrate cycle
	Ubiquinone biosynthesis	Pyruvate metabolism	Ephrin receptor signaling
Treadmil training versus no training		Protein ubiquitination pathway	Estrogen receptor signaling
		Amyloid processing	EIF2 signaling
		BMP signaling pathway	Regulation of eIF4 and p70S6K signaling
		Role of BRCA1 in DNA damage response	Glutamate metabolism
		Hereditary breast cancer signaling	Granzyme B signaling