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. 2014 Dec 1;14(19):1–72.

Table 27:

Summary of the Highest-Quality Evidence on Timing of Patient Care Planning Discussions

Outcome Results GRADE
Patient's QoL Earlier discussions were associated with greater QoL
adjusted β = 0.003, P = 0.006a
Low
Receiving chemotherapy at EoL Earlier discussions were associated with lower receipt of chemotherapy in the last 14 days of life
χ2: 17.057, P < 0.001a
Low
Receiving hospital care Earlier discussions were associated with less hospital care in the last 30 days of life
χ2: 55.905, P < 0.001a
Moderate
ICU care Earlier discussions were associated with less ICU care in the last 30 days of life
χ2: 16.606, P < 0.001a
Low
Receiving hospice care Earlier discussions were associated with receiving hospice care
χ2: 50.756, P < 0.001a
Moderate

Abbreviations: EoL, end of life; GRADE, Grading of Recommendations Assessment, Development, and Evaluation; ICU, intensive care unit; QoL, quality of life.

a

Statistically significant at P ≤ 0.05.