Table 1.
Analytical attributes of common target molecule assay types.
Sample throughput (per day) | Sensitivity (LLOD) | Flexibility | Linear response | Dynamic range | |
---|---|---|---|---|---|
Chromatography | 10–100 | mM | ++ | +++ | +++ |
Direct mass spectrometry | 100–1000 | nM | +++ | +++ | ++ |
Biosensors | 1000–10,000 | pM | + | + | + |
Screens | 1000–10,000 | nM | + | ++ | ++ |
Selection | 107+ | nM | + | + | + |
The optimal method for a given criteria is highlighted in bold.