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. 2015 Sep 7;3:135. doi: 10.3389/fbioe.2015.00135

Table 1.

Analytical attributes of common target molecule assay types.

Sample throughput (per day) Sensitivity (LLOD) Flexibility Linear response Dynamic range
Chromatography 10–100 mM ++ +++ +++
Direct mass spectrometry 100–1000 nM +++ +++ ++
Biosensors 1000–10,000 pM + + +
Screens 1000–10,000 nM + ++ ++
Selection 107+ nM + + +

The optimal method for a given criteria is highlighted in bold.