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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Dev Biol. 2015 Jun 24;405(1):1–9. doi: 10.1016/j.ydbio.2015.06.005

Figure 3. sh3bgr is necessary for sarcomere formation.

Figure 3

A-C. Stage 33 embryos were fixed and the coronal sections of somitic tissues were stained for α-actinin (Red) and MHC (Green). Knockdown of sh3bgr caused severe defects in the sarcomeres. Sh3bgr knockdown caused almost compete loss of sarcomere structures (B). Co-injection of Sh3bgr mRNA (1.5ng) with Sh3bgr-MO rescued sarcomere defects (C). D-F. Representative images of thick filaments. The fluorescent intensity plots of indicated muscle fibers are shown in (D’-F’). The average numbers of intact sarcomeres in each sample are shown in (G). Scale bar = 5μm