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. 2015 Sep 7;15:16. doi: 10.1186/s12900-015-0044-2

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© Tikhonova and Poerio. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — The ligand binding site of the free fatty acid 1–3 receptors a: the binding site in the FFA1 crystal structure; b and c: the binding site in the FFA1-based homology model of FFA2 and FFA3, respectively. The side chain of the binding site residues in FFAs is shown in blue, pink and green, respectively. H-bonding, π- π and π-cation interactions are shown in black, blue and green dotted lines, respectively