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. 2015 Aug 15;29(16):1707–1720. doi: 10.1101/gad.262568.115

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© 2015 Caserta et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 4. — Organ-selective cancer development in Pten^FV/+ mice. Histopathological analysis of the indicated tissues from Pten^FV/+ males and females was performed and scored as described in the Materials and Methods and Supplemental Figure 4. The table shows the percentage (%) of 18-mo-old Pten^FV/+ animals with cancer in the noted organs compared with the percentage of Pten^Δ/+ animals with cancer at 9 mo of age described previously (Wang et al. 2010). Carcinoma in control Pten^+/+ animals was not observed. (Total n) Number of animals analyzed for each organ site. Fisher's exact tests were used to compare differences between Pten^FV/+ and control Pten^+/+ animals. (*) P < 0.05.