Table 10. Prevalent cases and YLDs for 2013, percentage change, and percentage change of age-standardised rates between 1990 and 2013 for all causes.
| Prevalent cases in 2013 (× 1000) | Percentage change in prevalence from 1990 to 2013 | Percentage change in age-standardised prevalence from 1990 to 2013 | YLDs in 2013 (× 1000) | Percentage change in YLDs from 1990 to 2013 | Percentage change in age-standardised YLDs from 1990 to 2013 | |
|---|---|---|---|---|---|---|
| All causes | .. | .. | .. | 764 804·4 (572 379·6 to 990 467·0) | 42·3* (40·2 to 44·3) | −3·9* (−5·1 to −3·0) |
|
| ||||||
| Communicable, maternal, neonatal, and nutritional diseases | .. | .. | .. | 101 495·1 (71 533·1 to 138 458·0) | 7·6* (4·0 to 11·8) | −15·2* (−18·0 to −12·2) |
|
| ||||||
| HIV/AIDS and tuberculosis | .. | .. | .. | 7733·3 (5494·4 to 10 077·9) | 125·4* (113·7 to 141·0) | 47·1* (39·5 to 57·4) |
|
| ||||||
| Tuberculosis | 12 111·8 (11 791·6 to 12 452·0) | 51·6* (49·3 to 54·0) | −1·9* (−3·3 to −0·3) | 3669·7 (2519·7 to 4889·1) | 51·9* (48·6 to 55·2) | −1·3 (−3·4 to 0·7) |
| HIV/AIDS | .. | .. | .. | 4063·7 (2918·9 to 5327·4) | 301·7* (259·4 to 354·3) | 171·5* (142·0 to 208·7) |
| HIV/AIDS resulting in mycobacterial infection | 724·7 (496·0 to 922·5) | 275·7* (221·2 to 335·0) | 144·0* (107·3 to 184·1) | 268·3 (162·5 to 388·6) | 275·5* (218·1 to 335·1) | 144·6* (104·9 to 185·4) |
| HIV/AIDS resulting in other diseases | 28 506·6 (27 415·1 to 30 970·4) | 234·1* (217·8 to 262·8) | 134·5* (122·8 to 154·8) | 3795·3 (2726·7 to 4974·6) | 304·1* (257·2 to 361·0) | 174·0* (140·9 to 214·3) |
|
| ||||||
| Diarrhoea, lower respiratory, and other common infectious diseases | .. | .. | .. | 14 339·7 (10 108·4 to 19 541·9) | 0·2 (−2·8 to 4·6) | −18·5* (−18·5 to −13·6) |
|
| ||||||
| Diarrhoeal diseases | 42 409·6 (41 769·5 to 43 170·2) | −6·9* (−8·9 to −4·7) | −18·3* (−20·1 to −16·4) | 6854·2 (4701·9 to 9415·3) | −6·9* (−9·2 to −4·7) | −18·0* (−19·9 to −16·0) |
| Intestinal infectious diseases | .. | .. | .. | 203·7 (138·5 to 281·4) | −23·3* (−32·2 to −12·9) | −35·7* (−43·1 to −27·3) |
| Typhoid fever | 1198·3 (1103·3 to 1300·6) | −19·9* (−30·7 to −6·5) | −33·3* (−41·9 to −22·4) | 158·6 (109·0 to 223·3) | −19·0* (−30·5 to −4·2) | −32·3* (−41·8 to −20·5) |
| Paratyphoid fever | 735·9 (640·4 to 836·9) | −27·9* (−41·8 to −12·8) | −39·1* (−50·9 to −26·5) | 38·3 (24·0 to 57·6) | −27·1* (−41·6 to −9·7) | −38·4* (−50·3 to −23·9) |
| Other intestinal infectious diseases | .. | .. | .. | 6·8 (3·2 to 13·4) | −61·0* (−67·6 to −51·8) | −67·4* (−72·9 to −59·7) |
| Lower respiratory infections | 4473·3 (4374·7 to 4554·2) | −12·8* (−15·7 to −10·7) | −25·5* (−27·9 to −23·8) | 460·9 (310·5 to 642·7) | −14·1* (−17·4 to −11·7) | −26·1* (−28·9 to −24·2) |
| Upper respiratory infections | 244 327·5 (240 789·6 to 247 629·2) | 38·4* (35·7 to 41·5) | 6·3* (4·2 to 8·6) | 2863·1 (1597·9 to 4763·5) | 38·4* (35·4 to 41·6) | 6·6* (4·4 to 9·0) |
| Otitis media | 85 228·0 (82 190·3 to 88 667·4) | 14·4* (11·9 to 16·9) | −11·1* (−12·9 to −9·1) | 1696·4 (1017·6 to 2697·9) | 14·4* (11·4 to 17·6) | −10·1* (−12·2 to −7·7) |
| Meningitis | .. | .. | .. | 1679·1 (1165·8 to 2259·6) | −11·7* (−15·5 to −7·9) | −31·4* (−34·4 to −27·8) |
| Pneumococcal | 7805·6 (4929·9 to 11 605·5) | −5·5 (−11·3 to 1·8) | −30·7* (−34·7 to −25·6) | 698·1 (494·1 to 917·8) | −5·2 (−11·5 to 3·4) | −27·6* (−32·1 to −20·9) |
| Haemophilus influenzae type B | 3246·2 (1373·4 to 5962·2) | −19·1* (−26·4 to −12·0) | −38·5* (−43·6 to −32·2) | 375·5 (258·8 to 510·3) | −13·7* (−20·5 to −3·3) | −31·0* (−36·3 to −22·3) |
| Meningococcal | 1321·2 (490·6 to 2847·6) | −19·9* (−28·5 to −12·0) | −40·9* (−46·6 to −34·5) | 167·3 (106·3 to 251·6) | −17·1* (−25·0 to −8·0) | −37·2* (−42·5 to −29·3) |
| Other meningitis | 3595·2 (1901·7 to 6305·8) | −20·2* (−27·9 to −12·9) | −39·6* (−44·9 to −33·2) | 438·3 (299·2 to 604·2) | −17·4* (−23·3 to −11·9) | −35·2* (−39·7 to −30·7) |
| Encephalitis | 1739·8 (795·7 to 4003·7) | 3·1 (−16·5 to 12·6) | −27·5* (−41·1 to −21·1) | 229·1 (159·9 to 305·7) | 10·8* (4·7 to 17·9) | −20·6* (−25·0 to −15·4) |
| Diphtheria | 1·1 (0·7 to 2·0) | −62·1* (−83·4 to −15·4) | −65·7* (−84·6 to −25·0) | 0·1 (0·0 to 0·2) | −62·1* (−83·5 to −14·8) | −65·8* (−84·6 to −25·0) |
| Whooping cough | 2532·5 (1965·7 to 3239·2) | −30·0* (−30·6 to −29·4) | −32·5* (−33·1 to −31·8) | 125·5 (73·0 to 200·7) | −30·0* (−31·9 to −27·7) | −32·4* (−34·3 to −30·2) |
| Tetanus | 177·1 (117·5 to 265·7) | −87·1* (−92·5 to −77·9) | −90·1* (−94·2 to −82·9) | 13·2 (8·5 to 21·3) | −78·2* (−85·4 to −64·5) | −82·2* (−88·2 to −71·0) |
| Measles | 192·4 (150·4 to 242·9) | −77·1* (−79·2 to −74·9) | −78·0* (−80·1 to −75·9) | 17·3 (10·2 to 26·7) | −77·1* (−80·0 to −73·8) | −78·0* (−80·8 to −74·8) |
| Varicella and herpes zoster | 5715·8 (5587·6 to 5835·3) | 28·4* (25·5 to 31·7) | −2·4 (−4·9 to 0·3) | 197·2 (122·1 to 299·2) | 47·6* (41·1 to 54·5) | −1·8 (−5·7 to 2·7) |
|
| ||||||
| Neglected tropical diseases and malaria | .. | .. | .. | 20 100·7 (13 202·4 to 28 946·1) | −3·3 (−10·2 to 6·7) | −28·7* (−33·1 to −23·0) |
|
| ||||||
| Malaria | 351 051·1 (344 772·1 to 358 013·6) | 30·8* (28·4 to 33·2) | 3·0* (1·1 to 4·9) | 3170·5 (2132·3 to 4591·9) | 30·1* (25·2 to 35·0) | 7·8* (3·7 to 11·9) |
| Chagas disease | 9433·9 (9241·1 to 9628·4) | 22·4* (19·5 to 25·7) | −16·3* (−18·3 to −14·0) | 97·5 (64·9 to 137·0) | 33·6* (28·8 to 39·1) | −17·4* (−20·2 to −14·2) |
| Leishmaniasis | .. | .. | .. | 49·7 (25·5 to 90·4) | 134·7* (107·8 to 165·0) | 75·8* (58·0 to 97·3) |
| Visceral | 113·7 (94·1 to 140·9) | 35·1* (17·1 to 54·9) | 14·4 (−0·4 to 30·5) | 8·0 (5·2 to 12·3) | 35·8* (14·6 to 61·8) | 15·2 (−2·5 to 36·7) |
| Cutaneous and mucocutaneous | 3914·8 (3300·4 to 4669·6) | 174·2* (144·5 to 209·2) | 95·3* (75·2 to 119·9) | 41·7 (19·0 to 80·1) | 175·1* (146·0 to 210·9) | 97·1* (76·6 to 122·4) |
| African trypanosomiasis | 19·7 (10·6 to 34·3) | −71·1* (−75·3 to −65·9) | −79·5* (−82·4 to −75·8) | 5·4 (2·6 to 9·5) | −70·7* (−75·3 to −64·5) | −79·1* (−82·3 to −74·7) |
| Schistosomiasis | 290 627·9 (252 098·7 to 337 576·1) | 30·9* (22·9 to 51·9) | −3·7 (−9·7 to 11·8) | 2861·7 (1483·6 to 5467·2) | 34·1* (26·4 to 55·4) | 0·3 (−5·6 to 16·3) |
| Cysticercosis | 1030·8 (901·4 to 1185·6) | −26·3* (−37·3 to −10·0) | −50·2* (−57·5 to −39·0) | 310·4 (212·2 to 409·5) | −20·9* (−33·9 to −3·0) | −46·5* (−55·1 to −34·4) |
| Cystic echinococcosis | 849·2 (822·5 to 893·2) | −15·4* (−17·0 to −12·9) | −42·4* (−43·5 to −40·8) | 79·2 (54·9 to 110·3) | −15·3* (−18·9 to −11·0) | −42·0* (−44·3 to −39·2) |
| Lymphatic filariasis | 43 850·0 (36 940·8 to 52 905·8) | −32·1* (−39·1 to −24·7) | −53·3* (−58·0 to −48·4) | 2022·1 (1096·3 to 3294·4) | 5·9 (−15·7 to 26·4) | −32·3* (−46·0 to −19·3) |
| Onchocerciasis | 16 956·4 (11 477·5 to 26 789·4) | −31·2* (−39·8 to −21·9) | −51·5* (−57·6 to −45·3) | 1179·8 (556·6 to 1992·7) | −25·4* (−37·0 to −10·9) | −48·9* (−57·7 to −38·4) |
| Trachoma | 2428·8 (1924·2 to 2981·2) | −39·2* (−46·3 to −30·1) | −65·4* (−69·5 to −60·3) | 171·2 (115·3 to 241·7) | −37·2* (−43·0 to −30·4) | −64·2* (−67·5 to −60·5) |
| Dengue | 3485·5 (1283·7 to 7818·6) | 610·9* (606·3 to 615·5) | 447·3* (443·6 to 450·9) | 565·9 (186·4 to 1414·6) | 607·2* (558·4 to 659·5) | 446·8* (411·3 to 486·8) |
| Yellow fever | 2·1 (0·7 to 4·9) | −59·8* (−63·7 to −54·3) | −68·3* (−71·4 to −64·0) | 0·1 (0·0 to 0·2) | −59·8* (−63·7 to −54·3) | −68·3* (−71·4 to −64·0) |
| Rabies | 0·9 (0·7 to 1·1) | −39·8* (−54·3 to −27·3) | −55·2* (−65·1 to −46·1) | 0·1 (0·1 to 0·2) | −39·8* (−54·3 to −27·2) | −55·2* (−65·1 to −46·1) |
| Intestinal nematode infections | .. | .. | .. | 3691·6 (2185·8 to 5801·7) | −46·0* (−50·6 to −41·4) | −58·8* (−62·3 to −55·3) |
| Ascariasis | 804 370·1 (713 417·5 to 922 212·1) | −25·5* (−37·8 to −10·4) | −44·8* (−54·2 to −33·1) | 933·9 (516·6 to 1576·1) | −74·2* (−77·4 to −70·6) | −80·1* (−82·5 to −77·3) |
| Trichuriasis | 477 374·4 (441 256·8 to 518 365·1) | −11·6 (−28·7 to 4·9) | −34·4* (−47·8 to −21·0) | 576·0 (310·1 to 972·6) | −27·6* (−39·4 to −10·4) | −45·9* (−55·0 to −32·8) |
| Hookworm disease | 471 816·2 (437 049·6 to 511 318·8) | −5·1 (−20·2 to 9·7) | −30·1* (−41·6 to −18·4) | 2181·7 (1338·6 to 3354·5) | −10·9* (−17·3 to −4·4) | −32·9* (−38·0 to −27·7) |
| Food-borne trematodiases | 80 194·5 (64 648·1 to 96 212·4) | 51·1* (44·2 to 59·7) | −0·1 (−4·8 to 5·6) | 3634·8 (1160·2 to 7692·4) | 50·1* (40·6 to 60·0) | −1·8 (−8·1 to 4·9) |
| Other neglected tropical diseases | 59 705·9 (58 703·5 to 61 020·1) | −5·0 (−11·0 to 1·6) | −18·3* (−23·3 to −12·8) | 2260·7 (1473·6 to 3358·6) | −8·9* (−13·4 to −0·1) | −20·6* (−25·0 to −12·8) |
|
| ||||||
| Maternal disorders | .. | .. | .. | 1341·8 (924·5 to 1824·3) | 18·4* (8·2 to 27·4) | −15·0* (−21·9 to −8·4) |
|
| ||||||
| Maternal haemorrhage | 2027·4 (1932·4 to 2119·8) | 30·5* (22·2 to 39·2) | −2·1 (−8·1 to 4·4) | 69·5 (47·4 to 97·5) | 11·2 (−0·7 to 22·5) | −16·4* (−25·2 to −8·1) |
| Maternal sepsis and other maternal infections | 1781·4 (1235·4 to 2515·9) | −13·5* (−23·5 to −5·0) | −41·6* (−47·7 to −35·6) | 21·4 (11·6 to 36·3) | −22·4* (−35·3 to −9·7) | −43·2* (−51·8 to −34·5) |
| Maternal hypertensive disorders | 1277·6 (756·3 to 1978·8) | 3·5 (−0·4 to 10·2) | −21·3* (−23·8 to −17·2) | 64·7 (31·5 to 112·8) | 2·9 (−2·8 to 9·7) | −21·8* (−25·6 to −17·3) |
| Obstructed labour | 2902·1 (2600·1 to 3222·1) | 20·4* (12·9 to 27·5) | −14·8* (−19·8 to −10·2) | 951·5 (641·5 to 1304·0) | 20·9* (12·3 to 30·3) | −14·3* (−20·1 to −8·0) |
| Complications of abortion | 21·8 (14·6 to 29·7) | 11·5* (1·8 to 20·9) | −16·9* (−24·0 to −10·1) | 2·5 (1·4 to 4·0) | 12·0* (2·0 to 22·3) | −16·6* (−23·8 to −9·1) |
| Other maternal disorders | .. | .. | .. | 232·2 (155·8 to 343·7) | 22·1 (−14·3 to 62·2) | −10·5 (−37·3 to 18·5) |
|
| ||||||
| Neonatal disorders | .. | .. | .. | 12 648·8 (92 91·4 to 16 262·6) | 130·9* (108·5 to 158·7) | 80·5* (63·1 to 101·7) |
|
| ||||||
| Preterm birth complications | 56 272·0 (49 504·6 to 64 204·4) | 165·4* (143·0 to 192·5) | 98·9* (81·9 to 118·4) | 6689·7 (4914·1 to 8643·6) | 187·6* (166·9 to 210·3) | 119·4* (104·2 to 136·9) |
| Neonatal encephalopathy due to birth asphyxia and trauma | 22 858·6 (11 831·4 to 38 618·7) | 3·4 (−18·7 to 53·4) | −20·5 (−37·6 to 19·2) | 2388·1 (1783·6 to 3153·0) | 57·1* (32·4 to 84·0) | 25·6* (5·4 to 48·1) |
| Neonatal sepsis and other neonatal infections | 50·3 (16·5 to 106·6) | 110·0* (100·0 to 127·5) | 107·7* (97·8 to 125·0) | 6·6 (2·0 to 15·0) | 110·3* (97·4 to 128·1) | 108·1* (95·3 to 125·7) |
| Haemolytic disease and other neonatal jaundice | 4999·3 (3893·0 to 6792·3) | 132·9* (66·8 to 276·7) | 84·2* (33·6 to 197·8) | 1606·8 (1122·3 to 2234·6) | 112·4* (61·1 to 220·9) | 66·7* (28·2 to 151·9) |
| Other neonatal disorders | .. | .. | .. | 1957·6 (1334·4 to 2698·5) | 128·8* (82·2 to 189·1) | 80·3* (43·8 to 126·6) |
|
| ||||||
| Nutritional deficiencies | .. | .. | .. | 41 765·3 (27 678·6 to 60 351·7) | −9·4* (−12·0 to −7·0) | −26·1* (−27·8 to −24·5) |
|
| ||||||
| Protein-energy malnutrition | 20 756·9 (16 985·3 to 25 759·4) | −13·2 (−34·7 to 16·1) | −16·7 (−37·0 to 11·6) | 2574·3 (1588·3 to 3920·3) | −13·0 (−34·9 to 16·9) | −16·3 (−37·0 to 12·3) |
| Iodine deficiency | 115 602·4 (110 007·2 to 120 997·1) | −11·4* (−16·8 to −5·4) | −37·0* (−40·9 to −32·5) | 2075·0 (1294·6 to 3291·9) | −11·4* (−17·1 to −5·4) | −36·7* (−40·8 to −32·3) |
| Vitamin A deficiency | 3372·4 (2732·4 to 3926·3) | −19·4* (−24·4 to −14·6) | −34·9* (−39·3 to −31·1) | 153·7 (99·0 to 224·9) | −22·9* (−28·7 to −16·9) | −39·1* (−44·1 to −33·5) |
| Iron-deficiency anaemia | 1 208 216·4 (1 205 927·2 to 1 210 477·8) | −0·2 (−0·6 to 0·1) | −21·9* (−22·2 to −21·7) | 36 663·5 (24 371·0 to 53 084·7) | −8·6* (−9·8 to −7·1) | −25·8* (−26·7 to −24·9) |
| Other nutritional deficiencies | .. | .. | .. | 298·8 (157·9 to 535·4) | −43·8* (−63·9 to −10·0) | −45·7* (−65·2 to −13·1) |
|
| ||||||
| Other communicable, maternal, neonatal, and nutritional diseases | .. | .. | .. | 3565·4 (2282·3 to 5460·0) | 9·7* (5·6 to 15·8) | −13·4* (−15·8 to −9·9) |
|
| ||||||
| Sexually transmitted diseases excluding HIV | .. | .. | .. | 1383·8 (830·1 to 2404·6) | 38·0* (33·1 to 42·5) | −2·6 (−5·6 to 0·5) |
| Syphilis | 315·2 (306·5 to 324·5) | 1·5 (−2·5 to 6·4) | −37·1* (−39·5 to −34·3) | 58·4 (39·6 to 81·8) | 1·5 (−5·3 to 9·9) | −36·9* (−40·8 to −32·0) |
| Chlamydial infection | 147 846·5 (144 169·7 to 151 027·5) | 29·5* (24·8 to 33·4) | −5·5* (−8·8 to −2·8) | 646·5 (411·0 to 1019·4) | 37·1* (31·0 to 43·3) | 0·4 (−4·2 to 4·8) |
| Gonococcal infection | 32 726·1 (31 162·7 to 34 316·7) | 38·8* (29·6 to 47·6) | 4·8 (−2·0 to 11·4) | 225·4 (144·8 to 344·1) | 43·4* (29·1 to 61·0) | 7·9 (−2·6 to 20·9) |
| Trichomoniasis | 67 075·9 (62 762·6 to 72 764·6) | 45·6* (33·3 to 62·3) | 4·0 (−4·4 to 15·6) | 113·9 (45·1 to 242·9) | 45·5* (32·3 to 64·1) | 4·2 (−4·9 to 16·9) |
| Genital herpes | 1 176 494·5 (1 160 277·4 to 1 194 517·2) | 47·6* (44·7 to 50·6) | −5·3* (−7·1 to −3·5) | 311·6 (98·3 to 748·5) | 45·7* (40·8 to 49·6) | −4·8* (−6·8 to −2·6) |
| Other sexually transmitted diseases | 1248·2 (971·7 to 1612·4) | 1·9 (−4·1 to 10·2) | −31·9* (−35·8 to −26·5) | 27·9 (19·0 to 40·2) | 20·0* (9·2 to 32·4) | −16·9* (−24·3 to −8·1) |
| Hepatitis | .. | .. | .. | 444·1 (290·5 to 641·1) | 14·9* (12·1 to 17·5) | −17·3* (−19·4 to −15·3) |
| Hepatitis A | 7823·9 (7532·8 to 8115·3) | 11·9* (11·3 to 12·5) | −5·8* (−6·1 to −5·3) | 198·0 (128·3 to 287·8) | 25·9* (22·9 to 29·1) | −0·9 (−3·5 to 2·0) |
| Hepatitis B | 331 037·0 (325 359·6 to 336 638·4) | −5·5* (−7·9 to −3·4) | −32·1* (−33·7 to −30·6) | 172·6 (112·0 to 247·4) | 2·2 (−2·3 to 6·7) | −31·8* (−35·0 to −28·6) |
| Hepatitis C | 147 826·3 (145 520·7 to 150 080·2) | 16·0* (13·6 to 18·5) | −23·3* (−24·8 to −21·7) | 16·9 (11·0 to 24·3) | 15·5* (10·0 to 21·4) | −21·2* (−25·1 to −17·1) |
| Hepatitis E | 2188·2 (2083·3 to 2311·9) | 18·4* (11·3 to 26·9) | −10·9* (−16·2 to −4·6) | 56·6 (36·3 to 82·1) | 22·9* (12·1 to 34·4) | −8·6* (−16·4 to −0·0) |
| Leprosy | 658·8 (613·6 to 707·5) | 61·3* (54·0 to 69·6) | −1·5 (−6·0 to 3·5) | 39·7 (26·6 to 56·0) | 73·4* (61·0 to 86·6) | 5·7 (−1·5 to 13·4) |
| Other infectious diseases | 49 759·6 (48 625·5 to 51 029·0) | −4·9* (−7·8 to −2·0) | −20·6* (−22·9 to −18·2) | 1697·9 (1130·0 to 2469·8) | −7·5* (−11·7 to −1·1) | −19·8* (−23·4 to −14·6) |
|
| ||||||
| Non-communicable diseases | .. | .. | .. | 626 477·7 (465 287·7 to 806 573·8) | 54·2* (53·0 to 55·8) | 1·4* (0·7 to 2·2) |
|
| ||||||
| Neoplasms | .. | .. | .. | 6763·9 (4989·2 to 8715·9) | 82·5* (75·4 to 90·8) | 8·5* (4·4 to 13·5) |
|
| ||||||
| Oesophageal cancer | 840·5 (706·3 to 1015·2) | 56·2* (30·8 to 90·0) | −9·5 (−24·2 to 9·9) | 125·7 (88·9 to 167·2) | 49·6* (30·2 to 72·8) | −13·6* (−24·4 to −0·3) |
| Stomach cancer | 2532·1 (2347·7 to 2736·5) | 36·1* (25·8 to 47·4) | −21·0* (−26·9 to −14·7) | 290·4 (209·4 to 368·1) | 28·2* (19·1 to 38·3) | −25·7* (−30·9 to −20·0) |
| Liver cancer | .. | .. | .. | 190·6 (133·3 to 253·2) | 76·9* (55·6 to 102·0) | 4·5 (−7·6 to 19·0) |
| Liver cancer due to hepatitis B | 450·9 (373·3 to 538·8) | 91·2* (48·7 to 150·7) | 14·2 (−10·8 to 48·5) | 67·0 (46·3 to 89·9) | 70·7* (44·5 to 102·0) | 2·0 (−13·6 to 20·5) |
| Liver cancer due to hepatitis C | 512·6 (438·6 to 599·8) | 367·6* (284·7 to 478·2) | 168·7* (120·7 to 230·0) | 74·6 (52·6 to 99·9) | 310·5* (256·5 to 378·5) | 135·7* (106·8 to 174·3) |
| Liver cancer due to alcohol use | 197·2 (168·7 to 226·8) | 10·2 (−8·8 to 34·4) | −35·8* (−46·5 to −22·2) | 29·9 (20·7 to 40·1) | 2·0 (−10·3 to 16·3) | −40·4* (−47·6 to −32·1) |
| Liver cancer due to other causes | 121·5 (102·1 to 143·0) | −1·0 (−23·1 to 22·3) | −40·7* (−54·1 to −27·0) | 19·1 (13·1 to 25·6) | −9·8 (−24·0 to 4·4) | −45·8* (−54·2 to −37·5) |
| Larynx cancer | 899·8 (749·7 to 1069·8) | 41·6* (30·2 to 58·1) | −16·6* (−23·0 to −7·1) | 86·0 (60·0 to 115·2) | 32·8* (22·0 to 49·6) | −22·0* (−28·3 to −12·4) |
| Tracheal, bronchus, and lung cancer | 3227·4 (3039·7 to 3426·8) | 72·2* (61·9 to 82·1) | 0·8 (−5·4 to 6·5) | 467·4 (338·5 to 593·2) | 64·6* (54·9 to 72·9) | −3·7 (−9·3 to 1·2) |
| Breast cancer | 18 419·0 (17 740·6 to 19 141·4) | 126·9* (115·5 to 139·4) | 29·7* (23·5 to 36·5) | 1068·2 (760·8 to 1428·1) | 100·7* (86·6 to 114·3) | 15·7* (7·8 to 23·2) |
| Cervical cancer | 3180·8 (2623·1 to 3599·0) | 7·2 (−5·4 to 21·9) | −35·2* (−42·6 to −26·8) | 243·8 (169·8 to 333·0) | 8·3 (−3·5 to 22·3) | −34·6* (−41·7 to −26·6) |
| Uterine cancer | 2960·8 (2307·9 to 3516·4) | 66·5* (39·0 to 97·8) | −3·8 (−19·0 to 13·3) | 193·7 (123·7 to 273·6) | 62·9* (36·4 to 92·1) | −6·0 (−20·6 to 9·8) |
| Prostate cancer | 11 135·9 (10 002·5 to 13 123·4) | 178·8* (158·1 to 212·7) | 56·0* (44·6 to 75·0) | 893·7 (656·7 to 1192·5) | 164·2* (142·0 to 208·3) | 48·2* (35·8 to 72·9) |
| Colon and rectum cancer | 8591·6 (8252·7 to 8917·0) | 107·2* (97·8 to 115·6) | 18·4* (13·1 to 23·2) | 701·9 (512·7 to 899·1) | 95·5* (86·5 to 104·1) | 11·5* (6·3 to 16·5) |
| Lip and oral cavity cancer | 2416·5 (2044·4 to 2782·1) | 76·8* (56·3 to 103·4) | 2·9 (−9·0 to 18·2) | 206·9 (145·2 to 278·3) | 72·3* (52·9 to 98·2) | 0·0 (−11·1 to 14·6) |
| Nasopharynx cancer | 501·1 (422·3 to 596·2) | 29·7* (5·8 to 58·5) | −21·1* (−35·7 to −4·0) | 47·9 (33·1 to 64·3) | 25·9* (5·6 to 49·6) | −23·5* (−36·0 to −9·4) |
| Other pharynx cancer | 752·5 (644·9 to 857·1) | 81·2* (53·9 to 109·4) | 4·7 (−10·9 to 20·6) | 66·0 (45·5 to 88·5) | 75·5* (51·3 to 101·5) | 1·4 (−12·6 to 16·3) |
| Gallbladder and biliary tract cancer | 158·3 (135·9 to 177·6) | 46·7* (29·3 to 62·7) | −17·1* (−27·2 to −8·0) | 39·1 (27·0 to 52·1) | 39·8* (22·7 to 54·9) | −20·5* (−30·6 to −11·5) |
| Pancreatic cancer | 384·3 (355·9 to 412·9) | 100·5* (84·2 to 117·8) | 14·3* (5·2 to 24·5) | 73·6 (52·1 to 96·2) | 92·1* (80·6 to 103·7) | 9·9* (3·1 to 16·8) |
| Malignant skin melanoma | 2341·5 (1808·4 to 3151·3) | 87·9* (65·9 to 107·1) | 13·9* (0·5 to 24·9) | 137·9 (91·7 to 205·0) | 80·8* (59·5 to 99·7) | 9·1 (−3·8 to 20·2) |
| Non-melanoma skin cancer | 5529·6 (4962·1 to 6204·9) | 108·8* (78·8 to 141·7) | 18·2* (0·3 to 36·9) | 126·2 (82·5 to 188·1) | 152·8* (116·5 to 200·2) | 42·5* (21·3 to 70·3) |
| Ovarian cancer | 1053·8 (975·7 to 1145·0) | 68·3* (56·1 to 82·3) | −0·9 (−8·1 to 7·0) | 134·9 (97·0 to 174·6) | 65·1* (52·0 to 79·7) | −2·9 (−10·7 to 4·8) |
| Testicular cancer | 556·0 (423·6 to 681·0) | 60·8* (32·1 to 84·9) | 9·4 (−9·7 to 25·6) | 34·3 (22·2 to 49·0) | 57·6* (30·8 to 80·5) | 6·6 (−10·8 to 21·9) |
| Kidney cancer | 1960·6 (1829·8 to 2099·4) | 117·3* (104·5 to 131·6) | 31·8* (23·9 to 40·4) | 139·2 (99·2 to 185·8) | 109·7* (97·0 to 123·5) | 26·1* (18·2 to 34·3) |
| Bladder cancer | 2359·6 (2077·2 to 2563·2) | 58·5* (49·8 to 69·1) | −8·8* (−14·2 to −2·8) | 179·8 (132·1 to 235·5) | 52·5* (44·1 to 62·5) | −12·8* (−17·8 to −6·9) |
| Brain and nervous system cancer | 1193·2 (1010·6 to 1373·3) | 52·2* (28·6 to 70·9) | 7·2 (−7·2 to 18·9) | 121·9 (87·1 to 165·1) | 55·4* (34·3 to 71·8) | 5·6 (−6·7 to 15·9) |
| Thyroid cancer | 2179·4 (1815·3 to 2509·2) | 100·2* (74·8 to 129·9) | 24·4* (9·6 to 41·3) | 127·6 (85·7 to 180·9) | 94·9* (71·3 to 122·4) | 19·7* (6·6 to 35·6) |
| Mesothelioma | 50·4 (44·2 to 57·6) | 94·7* (65·9 to 110·9) | 12·9 (−4·3 to 22·0) | 10·8 (7·4 to 14·4) | 96·6* (66·5 to 113·0) | 14·1 (−4·4 to 23·5) |
| Hodgkin’s lymphoma | 725·3 (625·0 to 997·2) | −12·7 (−30·9 to 59·0) | −34·7 (−46·7 to 16·7) | 57·5 (38·7 to 82·1) | −12·0 (−26·8 to 56·4) | −36·2 (−45·7 to 11·0) |
| Non-Hodgkin lymphoma | 2956·4 (2448·0 to 3253·1) | 121·7* (82·7 to 142·0) | 38·4* (12·3 to 50·7) | 216·2 (151·6 to 292·6) | 112·2* (75·7 to 131·1) | 31·4* (6·4 to 43·3) |
| Multiple myeloma | 427·4 (349·3 to 528·8) | 107·8* (78·1 to 137·1) | 19·0* (1·3 to 36·9) | 86·3 (59·7 to 114·9) | 98·6* (68·9 to 124·1) | 13·4 (−4·5 to 28·6) |
| Leukaemia | 2117·3 (1978·7 to 2248·2) | 44·3* (24·8 to 58·6) | 6·7 (−4·6 to 15·6) | 249·6 (182·7 to 320·2) | 52·1* (38·4 to 63·8) | 4·1 (−4·0 to 11·4) |
| Other neoplasms | 6785·0 (5938·1 to 7417·5) | 185·5* (104·5 to 215·4) | 93·2* (47·0 to 113·0) | 446·8 (312·5 to 596·4) | 172·3* (102·3 to 199·0) | 78·3* (39·6 to 97·0) |
|
| ||||||
| Cardiovascular diseases | .. | .. | .. | 21 177·0 (14 947·8 to 28 436·7) | 89·2* (69·1 to 108·7) | 10·3 (−1·0 to 21·3) |
|
| ||||||
| Rheumatic heart disease | 32 903·9 (31 608·5 to 34 023·7) | 62·8* (51·3 to 72·0) | 13·5* (6·0 to 19·7) | 1821·3 (1211·3 to 2530·8) | 60·8* (47·5 to 73·7) | 9·5 (−0·3 to 18·1) |
| Ischaemic heart disease | 92 936·7 (90 091·9 to 95 860·8) | 64·7* (57·0 to 72·2) | −5·2* (−9·6 to −1·0) | 5804·1 (4055·2 to 7902·3) | 67·5* (58·8 to 76·6) | −4·0 (−8·8 to 1·2) |
| Cerebrovascular disease | .. | .. | .. | 3743·6 (2669·9 to 4843·9) | 83·5* (75·9 to 93·5) | 5·0* (0·5 to 11·2) |
| Ischaemic stroke | 18 305·5 (17 767·4 to 18 920·7) | 81·5* (72·6 to 92·7) | 2·4 (−2·8 to 9·1) | 2650·1 (1875·1 to 3492·3) | 81·8* (72·6 to 93·3) | 3·0 (−2·2 to 9·9) |
| Haemorrhagic stroke | 7363·5 (7139·7 to 7616·1) | 88·9* (80·6 to 98·6) | 10·2* (5·4 to 16·1) | 1093·5 (759·0 to 1438·1) | 88·5* (79·7 to 99·0) | 10·6* (5·6 to 17·1) |
| Hypertensive heart disease | 10 893·7 (10 526·7 to 11 246·4) | 112·8* (101·6 to 123·9) | 19·1* (12·7 to 25·4) | 1193·9 (844·9 to 1633·9) | 113·8* (102·8 to 124·9) | 20·0* (13·7 to 26·3) |
| Cardiomyopathy and myocarditis | 7993·0 (7738·3 to 8269·3) | 85·0* (77·9 to 93·0) | 8·5* (4·3 to 13·4) | 865·7 (591·5 to 1159·6) | 86·8* (79·0 to 95·1) | 9·8* (5·2 to 14·8) |
| Atrial fibrillation and flutter | 11 178·6 (10 655·1 to 11 683·7) | 63·6* (53·9 to 71·4) | −10·3* (−15·6 to −5·8) | 857·8 (603·7 to 1177·4) | 64·2* (54·3 to 71·9) | −9·7* (−15·1 to −5·2) |
| Peripheral vascular disease | 185 137·2 (172 555·7 to 196 597·2) | 78·0* (59·9 to 91·2) | −0·1 (−9·9 to 6·7) | 127·7 (62·4 to 223·8) | 49·6* (31·2 to 64·3) | −19·7* (−29·5 to −12·0) |
| Endocarditis | 310·3 (252·1 to 361·0) | 71·7* (55·9 to 86·2) | 4·6 (−5·1 to 13·6) | 32·5 (21·2 to 46·7) | 77·4* (59·7 to 96·2) | 7·0 (−3·9 to 18·4) |
| Other cardiovascular and circulatory diseases | 95 225·2 (67 433·2 to 121 733·8) | 130·2* (53·9 to 234·7) | 36·4 (−8·6 to 98·7) | 6730·4 (3926·1 to 10 097·9) | 131·2* (53·7 to 236·5) | 37·1 (−8·4 to 99·7) |
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| Chronic respiratory diseases | .. | .. | .. | 38 618·7 (26 864·7 to 51 458·3) | 55·1* (50·3 to 60·6) | 0·0 (−2·5 to 2·8) |
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| Chronic obstructive pulmonary disease | 328 503·6 (317 289·1 to 339 461·0) | 65·1* (63·8 to 66·3) | 0·5 (−0·2 to 1·2) | 26 131·3 (17 785·3 to 35 786·9) | 72·3* (67·4 to 78·6) | 5·5* (2·7 to 9·3) |
| Pneumoconiosis | .. | .. | .. | 50·8 (36·0 to 69·0) | 96·9* (89·2 to 103·3) | 17·3* (12·5 to 21·3) |
| Silicosis | 56·2 (52·6 to 59·6) | 49·8* (47·3 to 52·3) | −11·8* (−13·3 to −10·5) | 10·7 (6·9 to 15·1) | 49·9* (47·2 to 52·3) | −11·8* (−13·3 to −10·5) |
| Asbestosis | 14·8 (14·0 to 15·5) | 67·5* (64·0 to 71·4) | −0·7 (−2·8 to 1·7) | 2·8 (1·8 to 3·9) | 68·1* (64·6 to 72·1) | −0·4 (−2·5 to 2·0) |
| Coal workers’ pneumoconiosis | 36·4 (34·6 to 38·1) | 55·1* (53·1 to 56·8) | −6·9* (−8·0 to −5·9) | 6·8 (4·6 to 9·8) | 55·1* (53·0 to 56·9) | −6·9* (−8·1 to −5·9) |
| Other pneumoconiosis | 164·9 (154·0 to 174·3) | 144·2* (137·9 to 150·3) | 47·4* (44·0 to 51·1) | 30·5 (19·9 to 43·9) | 141·8* (136·0 to 148·2) | 45·7* (42·3 to 49·7) |
| Asthma | 241 694·7 (238 151·1 to 245 464·6) | 32·1* (29·5 to 34·9) | −5·5* (−7·2 to −3·5) | 10 595·8 (6924·6 to 15 102·0) | 31·6* (28·9 to 34·6) | −5·3* (−7·2 to −3·2) |
| Interstitial lung disease and pulmonary sarcoidosis | 595·0 (569·1 to 622·5) | 69·8* (58·9 to 78·9) | 5·1 (−1·5 to 10·6) | 80·7 (50·7 to 117·9) | 70·9* (59·5 to 80·2) | 5·4 (−1·5 to 11·2) |
| Other chronic respiratory diseases | .. | .. | .. | 1760·0 (1150·0 to 2617·9) | 8·4 (−4·6 to 26·4) | −32·8* (−40·7 to −21·8) |
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| Cirrhosis | .. | .. | .. | 544·6 (381·1 to 750·4) | 29·2* (25·5 to 33·2) | −14·9* (−17·2 to −12·6) |
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| Cirrhosis due to hepatitis B | 869·0 (813·2 to 923·0) | 21·6* (11·4 to 30·2) | −20·8* (−27·2 to −15·3) | 143·2 (98·8 to 197·7) | 20·9* (9·1 to 31·6) | −21·0* (−28·1 to −13·9) |
| Cirrhosis due to hepatitis C | 884·9 (837·2 to 947·7) | 60·5* (52·0 to 74·4) | 1·6 (−3·6 to 10·5) | 144·9 (100·8 to 201·3) | 59·9* (49·8 to 75·3) | 1·6 (−4·2 to 11·4) |
| Cirrhosis due to alcohol use | 801·5 (746·6 to 864·3) | 10·0* (1·1 to 21·4) | −33·4* (−38·6 to −27·1) | 131·2 (89·3 to 180·1) | 10·3 (−0·2 to 22·7) | −33·1* (−39·2 to −26·0) |
| Cirrhosis due to other causes | 742·0 (693·9 – 789·5) | 33·6* (24·4 to 46·3) | 3·6 (−3·5 to 13·2) | 125·3 (85·6 to 175·1) | 33·3* (20·7 to 50·5) | 3·5 (−6·3 to 16·4) |
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| Digestive diseases | .. | .. | .. | 8457·9 (6066·5 to 11 283·9) | 24·4* (19·9 to 28·8) | −21·9* (−24·7 to −19·2) |
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| Peptic ulcer disease | 35 515·2 (33 962·5 to 36 907·1) | −5·4* (−7·9 to −2·5) | −45·8* (−47·1 to −44·1) | 1268·6 (873·2 to 1774·5) | −1·4 (−5·9 to 3·7) | −43·2* (−45·5 to −40·3) |
| Gastritis and duodenitis | 64 799·9 (63 317·5 to 66 212·6) | 11·4* (7·8 to 14·9) | −26·7* (−28·7 to −24·7) | 2384·2 (1617·0 to 3388·7) | 6·3* (1·7 to 10·3) | −27·6* (−30·4 to −25·2) |
| Appendicitis | 621·7 (546·4 to 699·6) | 17·0* (1·0 to 37·2) | −14·6 (−25·4 to 0·0) | 190·2 (126·9 to 263·1) | 17·4 (−1·0 to 39·2) | −13·6 (−26·7 to 1·8) |
| Paralytic ileus and intestinal obstruction | 114·6 (111·4 to 117·6) | 50·4* (44·7 to 56·3) | 4·6* (1·2 to 8·0) | 35·1 (23·8 to 47·5) | 49·2* (41·2 to 57·4) | 4·7 (−0·6 to 10·6) |
| Inguinal, femoral, and abdominal hernia | 25 393·4 (24 084·5 to 26 361·0) | 45·7* (36·0 to 53·1) | −10·5* (−16·1 to −5·9) | 262·3 (129·4 to 490·8) | 45·7* (35·8 to 53·1) | −9·9* (−15·6 to −5·3) |
| Inflammatory bowel disease | 10 575·9 (10 410·1 to 10 737·6) | 75·7* (72·7 to 78·6) | 9·6* (7·7 to 11·4) | 2223·2 (1544·1 to 3028·2) | 75·6* (71·5 to 79·5) | 10·1* (7·6 to 12·5) |
| Vascular intestinal disorders | 35·3 (33·2 to 38·6) | 69·9* (58·7 to 81·6) | −0·7 (−7·6 to 6·5) | 10·8 (7·2 to 14·6) | 68·8* (54·1 to 83·7) | −0·2 (−9·7 to 9·8) |
| Gallbladder and biliary diseases | 5893·8 (5737·7 to 6119·0) | 37·0* (32·6 to 43·9) | −18·2* (−20·8 to −14·3) | 614·9 (428·8 to 826·8) | 36·9* (31·5 to 43·6) | −17·9* (−21·0 to −14·3) |
| Pancreatitis | 1972·8 (1951·7 to 1997·4) | 70·8* (68·4 to 73·3) | 6·9* (5·5 to 8·4) | 579·8 (398·9 to 771·6) | 70·5* (65·1 to 75·8) | 7·3* (4·1 to 10·5) |
| Other digestive diseases | .. | .. | .. | 888·8 (612·7 to 1228·4) | 5·9 (−8·5 to 17·1) | −34·2* (−43·3 to −27·2) |
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| Neurological disorders | .. | .. | .. | 59 360·1 (41 036·0 to 80 871·8) | 59·6* (54·8 to 64·5) | 5·0* (2·4 to 7·9) |
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| Alzheimer’s disease and other dementias | 53 050·5 (51 663·7 to 54 359·8) | 88·5* (82·1 to 95·0) | −0·7 (−4·0 to 2·8) | 7773·6 (5703·1 to 9867·3) | 91·8* (85·3 to 98·5) | 0·0 (−3·5 to 3·8) |
| Parkinson’s disease | 5866·3 (4777·2 to 6950·0) | 80·9* (77·7 to 83·6) | 2·1* (0·4 to 3·5) | 694·8 (468·5 to 964·1) | 81·2* (77·3 to 85·2) | 2·7* (0·6 to 4·6) |
| Epilepsy | 21 712·0 (20 160·3 to 23 108·4) | 31·6* (20·2 to 43·8) | −2·5 (−10·8 to 6·7) | 7544·2 (5164·1 to 9925·9) | 40·5* (28·5 to 56·5) | 4·4 (−4·5 to 15·9) |
| Multiple sclerosis | 2293·6 (2238·9 to 2345·6) | 117·2* (110·0 to 124·0) | 35·4* (30·7 to 39·5) | 754·6 (547·6 to 951·0) | 116·1* (106·3 to 125·7) | 35·1* (29·0 to 41·1) |
| Migraine | 848 366·5 (831 034·6 to 864 852·1) | 46·1* (41·4 to 50·1) | 0·3 (−2·8 to 3·0) | 28 898·1 (17 585·8 to 42 420·1) | 46·1* (41·4 to 50·5) | 0·8 (−2·4 to 3·7) |
| Tension-type headache | 1 561 446·5 (1 537 571·4 to 1 585 765·8) | 45·5* (41·9 to 49·4) | 0·0 (−2·4 to 2·6) | 2363·2 (1151·9 to 4155·0) | 45·5* (41·7 to 49·5) | 0·3 (−2·1 to 2·9) |
| Medication overuse headache | 62 899·3 (43 143·0 to 80 656·0) | 120·2* (109·5 to 133·8) | 42·8* (35·9 to 51·9) | 9845·7 (5777·9 to 15 100·3) | 120·2* (109·3 to 133·7) | 43·3* (36·2 to 52·4) |
| Other neurological disorders | 11·6 (10·0 to 13·3) | 45·9* (36·0 to 56·3) | 0·9 (−5·6 to 7·9) | 1485·8 (1056·6 to 1918·6) | 31·4* (12·7 to 40·4) | −29·6* (−39·2 to −24·8) |
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| Mental and substance use disorders | .. | .. | .. | 161 811·9 (116 057·8 to 210 256·0) | 45·0* (42·9 to 47·2) | 1·0* (0·3 to 1·9) |
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| Schizophrenia | 23 600·6 (22 170·6 to 25 038·7) | 52·1* (50·3 to 53·6) | −1·5* (−2·4 to −0·6) | 15 204·4 (11 169·3 to 18 188·6) | 52·1* (50·3 to 54·1) | −1·1 (−2·2 to 0·1) |
| Alcohol use disorders | 76 896·6 (73 454·0 to 80 491·9) | 34·4* (32·3 to 36·4) | −7·6* (−8·8 to −6·5) | 7653·6 (5150·7 to 10 952·3) | 34·3* (32·0 to 36·6) | −7·5* (−8·8 to −6·1) |
| Drug use disorders | .. | .. | .. | 12 222·4 (8513·1 to 16 172·8) | 41·3* (36·3 to 46·3) | 0·6 (−2·4 to 3·8) |
| Opioid use disorders | 14 071·8 (11 103·0 to 181 39·2) | 58·9* (54·4 to 62·8) | 6·4* (3·0 to 9·5) | 5849·5 (3907·9 to 8184·0) | 59·1* (54·0 to 63·6) | 6·7* (3·2 to 10·2) |
| Cocaine use disorders | 7384·6 (7216·3 to 7549·3) | 32·1* (28·4 to 35·8) | −5·9* (−8·5 to −3·3) | 1012·9 (666·9 to 1430·2) | 32·1* (27·2 to 37·1) | −5·7* (−9·2 to −2·3) |
| Amphetamine use disorders | 14 922·9 (14 490·6 to 15 370·7) | 26·4* (21·2 to 31·3) | −4·1* (−8·0 to −0·6) | 1961·0 (1233·0 to 2832·9) | 26·6* (20·8 to 32·2) | −3·8 (−8·1 to 0·3) |
| Cannabis use disorders | 13 625·0 (12 429·2 to 14 938·0) | 22·4* (20·6 to 24·0) | −6·5* (−7·6 to −5·5) | 395·6 (261·2 to 576·2) | 22·4* (19·0 to 26·1) | −6·4* (−8·9 to −3·7) |
| Other drug use disorders | .. | .. | .. | 3003·3 (1998·9 to 4164·5) | 28·5* (21·5 to 36·5) | −4·4 (−9·7 to 1·4) |
| Depressive disorders | .. | .. | .. | 61 632·8 (41 353·8 to 85 621·4) | 53·6* (49·6 to 58·4) | 4·0* (2·2 to 5·6) |
| Major depressive disorder | 253 314·2 (208 457·2 to 299 691·3) | 53·4* (49·0 to 58·9) | 4·2* (2·4 to 6·2) | 51 783·9 (33 888·2 to 73 665·8) | 53·4* (48·8 to 59·2) | 4·7* (2·7 to 6·7) |
| Dysthymia | 102 409·6 (91 246·2 to 113 441·2) | 54·6* (52·4 to 57·2) | −0·3 (−1·2 to 0·7) | 9848·9 (6586·6 to 14 166·0) | 54·6* (52·1 to 57·2) | 0·1 (−1·0 to 1·2) |
| Bipolar disorder | 48 778·4 (43 498·9 to 54 371·2) | 49·1* (46·7 to 52·2) | 0·9 (−0·4 to 2·4) | 9911·1 (6260·6 to 14 791·0) | 49·2* (46·4 to 52·5) | 1·3 (−0·4 to 2·9) |
| Anxiety disorders | 265 610·1 (213 015·1 to 318 817·0) | 42·4* (36·6 to 46·8) | −0·5 (−1·7 to 0·8) | 24 355·8 (16 148·6 to 35 139·0) | 42·1* (36·4 to 46·5) | −0·2 (−1·6 to 1·3) |
| Eating disorders | .. | .. | .. | 1820·0 (1154·5 to 2720·3) | 27·6* (23·7 to 32·1) | −1·2 (−4·2 to 1·7) |
| Anorexia nervosa | 2063·6 (1683·5 to 2535·0) | 35·4* (31·1 to 40·7) | 5·5* (2·2 to 9·2) | 440·4 (285·5 to 648·3) | 35·9* (30·2 to 41·8) | 6·0* (1·7 to 10·3) |
| Bulimia nervosa | 6537·9 (4917·2 to 8857·6) | 24·8* (20·4 to 29·2) | −3·7* (−6·9 to −0·8) | 1379·7 (850·7 to 2136·6) | 25·1* (20·2 to 30·2) | −3·4 (−7·1 to 0·1) |
| Autistic spectrum disorders | .. | .. | .. | 8449·0 (5888·1 to 11 458·7) | 33·8* (32·7 to 34·9) | 0·7 (−0·0 to 1·5) |
| Autism | 21 716·7 (20 731·8 to 22 713·5) | 34·1* (33·5 to 34·8) | 0·3* (0·1 to 0·6) | 5345·0 (3583·6 to 7309·9) | 33·9* (32·4 to 35·5) | 0·7 (−0·3 to 1·8) |
| Asperger’s syndrome | 31 100·1 (29 251·7 to 32 905·1) | 33·7* (32·9 to 34·5) | 0·4* (0·3 to 0·5) | 3104·0 (2169·6 to 4325·0) | 33·6* (32·3 to 35·0) | 0·7 (−0·1 to 1·5) |
| Attention-deficit or hyperactivity disorder | 39 343·5 (36 574·2 to 42 093·6) | 13·8* (12·8 to 14·9) | −0·5 (−1·3 to 0·5) | 479·9 (287·4 to 745·8) | 13·9* (12·1 to 16·0) | −0·3 (−1·9 to 1·5) |
| Conduct disorder | 51 109·7 (48 006·9 to 54 557·0) | 16·3* (15·4 to 17·2) | 2·2* (1·4 to 3·1) | 6159·0 (3868·2 to 8911·6) | 16·5* (15·0 to 18·0) | 2·4* (1·1 to 3·8) |
| Idiopathic intellectual disability | 94 672·8 (75 906·5 to 116 664·7) | 22·6* (12·7 to 35·8) | −5·8 (−13·5 to 4·4) | 4666·7 (3084·8 to 6640·0) | 22·0* (12·1 to 35·0) | −6·1 (−13·9 to 3·8) |
| Other mental and substance use disorders | 124 042·9 (116 741·4 to 131 001·8) | 52·3* (50·9 to 53·8) | 0·2* (0·1 to 0·3) | 9257·2 (6277·9 to 12411·5) | 52·3* (50·5 to 54·1) | 0·6 (−0·1 to 1·3) |
|
| ||||||
| Diabetes, urogenital, blood, and endocrine diseases | .. | .. | .. | 65 561·4 (46 201·5 to 87 834·5) | 72·7* (69·2 to 76·6) | 14·1* (11·9 to 16·4) |
|
| ||||||
| Diabetes mellitus | 409 967·0 (381 806·3 to 432 038·4) | 132·9* (123·7 to 142·4) | 44·8* (38·5 to 51·3) | 29 518·1 (20 419·1 to 40 169·3) | 135·7* (127·2 to 143·7) | 43·4* (37·9 to 48·5) |
| Acute glomerulonephritis | 37·7 (35·1 to 40·5) | −3·4* (−6·0 to −1·2) | −22·2* (−24·2 to −20·6) | 1·9 (1·2 to 2·8) | −3·3* (−6·0 to −1·1) | −22·2* (−24·2 to −20·6) |
| Chronic kidney disease | .. | .. | .. | 12 347·3 (9101·6 to 15 814·9) | 49·5* (43·4 to 53·9) | −2·8* (−6·4 to −0·4) |
| Chronic kidney disease due to diabetes mellitus | 88 710·9 (71 150·1 to 111 417·2) | 82·4* (58·6 to 96·8) | 11·9 (−3·6 to 21·2) | 2491·8 (1802·9 to 3220·7) | 80·5* (65·7 to 92·6) | 10·6* (2·0 to 17·7) |
| Chronic kidney disease due to hypertension | 101 253·4 (81 410·4 to 129 993·0) | 26·8* (18·3 to 34·9) | −10·7* (−17·6 to −5·3) | 2635·3 (1915·3 to 3415·5) | 23·1* (16·3 to 33·2) | −22·4* (−26·9 to −16·3) |
| Chronic kidney disease due to glomerulonephritis | 108 860·9 (88 330·3 to 135 481·9) | 32·7* (17·3 to 41·3) | −13·5* (−25·6 to −6·6) | 2495·9 (1809·0 to 3252·0) | 33·9* (25·6 to 43·3) | −6·9* (−11·9 to −0·5) |
| Chronic kidney disease due to other causes | 173 090·7 (142 395·9 to 213 010·4) | 53·9* (43·5 to 63·6) | 3·1 (−5·9 to 10·1) | 4724·3 (3503·0 to 6063·2) | 63·4* (55·9 to 71·9) | 6·9* (0·9 to 12·7) |
| Urinary diseases and male infertility | .. | .. | .. | 4880·3 (3212·9 to 7017·1) | 83·8* (77·8 to 91·1) | 8·5* (5·1 to 12·4) |
| Interstitial nephritis and urinary tract infections | 1753·7 (1730·2 to 1775·3) | 67·5* (64·6 to 70·9) | 16·2* (14·3 to 18·4) | 58·1 (36·4 to 85·6) | 66·8* (59·9 to 74·7) | 16·4* (11·8 to 21·3) |
| Urolithiasis | 80 622·5 (61 562·7 to 103 069·9) | 101·9* (89·6 to 113·3) | 20·0* (12·9 to 26·1) | 661·8 (411·4 to 984·0) | 95·8* (83·0 to 109·3) | 20·4* (13·0 to 27·6) |
| Benign prostatic hyperplasia | 99 148·4 (97 356·1 to 100 911·6) | 79·3* (75·4 to 83·7) | 3·0* (0·8 to 5·6) | 3552·9 (2316·5 to 4993·7) | 80·0* (75·9 to 84·5) | 3·6* (1·3 to 6·3) |
| Male infertility due to other causes | 39 276·2 (36 950·6 to 41 618·7) | 44·0* (33·3 to 55·3) | 2·9 (−4·8 to 11·0) | 258·6 (111·8 to 531·4) | 43·6* (32·3 to 56·6) | 3·0 (−5·1 to 12·0) |
| Other urinary diseases | .. | .. | .. | 348·9 (175·8 to 544·0) | 195·7* (94·2 to 241·5) | 86·0* (23·4 to 114·7) |
| Gynaecological diseases | .. | .. | .. | 9131·4 (5982·5 to 13 595·8) | 44·5* (40·3 to 49·3) | −3·5* (−6·1 to −0·5) |
| Uterine fibroids | 171 005·4 (158 155·9 to 182 513·5) | 62·5* (61·2 to 63·8) | −1·8* (−2·3 to −1·2) | 2164·7 (1242·3 to 3677·9) | 36·6* (29·4 to 43·6) | −14·3* (−18·3 to −10·6) |
| Polycystic ovarian syndrome | 122 310·6 (119 572·7 to 124 929·3) | 51·1* (46·6 to 55·6) | 2·3 (−0·6 to 5·2) | 1191·2 (562·3 to 2227·4) | 51·7* (47·1 to 56·4) | 3·0* (0·1 to 6·1) |
| Female infertility due to other causes | 34 678·6 (31 103·9 to 38 009·3) | 58·3* (44·8 to 72·4) | 10·7* (1·7 to 20·3) | 191·9 (75·2 to 399·1) | 56·9* (42·4 to 71·6) | 11·0* (1·0 to 21·0) |
| Endometriosis | 14 661·2 (14 230·8 to 15 094·4) | 47·9* (41·9 to 53·5) | −1·6 (−5·6 to 2·1) | 1359·6 (906·4 to 1861·5) | 48·1* (42·1 to 54·3) | −1·3 (−5·3 to 2·8) |
| Genital prolapse | 343 707·8 (336 958·8 to 350 327·4) | 57·0* (53·0 to 61·5) | −0·9 (−3·3 to 1·7) | 1094·2 (534·5 to 2041·0) | 57·1* (52·9 to 61·7) | −0·7 (−3·3 to 2·1) |
| Premenstrual syndrome | 302 731·7 (284 373·1 to 321 829·6) | 53·8* (40·3 to 67·9) | 9·2 (−0·1 to 19·4) | 2548·6 (1581·3 to 3777·0) | 54·0* (40·7 to 67·9) | 9·5* (0·1 to 19·5) |
| Other gynaecological diseases | 20 758·0 (19 699·4 to 21 792·8) | 15·7* (6·9 to 26·4) | −19·3* (−25·6 to −11·8) | 581·3 (395·7 to 826·6) | 4·2 (−4·6 to 21·3) | −27·2* (−33·5 to −14·7) |
| Haemoglobinopathies and haemolytic anaemias | .. | .. | .. | 7071·9 (4730·8 to 10107·0) | 23·2* (20·7 to 26·5) | −2·3 (−4·2 to 0·3) |
| Thalassaemias | 766·7 (691·8 to 849·8) | 11·6* (8·5 to 19·1) | −2·5 (−5·1 to 3·8) | 61·9 (42·1 to 88·0) | 10·2* (1·8 to 22·1) | −4·2 (−11·3 to 5·8) |
| Thalassaemia trait | 207 561·8 (192 411·3 to 228 437·6) | 37·3* (34·7 to 39·6) | 2·7* (0·5 to 4·5) | 3769·6 (2508·9 to 5442·2) | 34·6* (31·0 to 38·8) | 5·9* (3·1 to 9·3) |
| Sickle cell disorders | 3250·4 (3091·7 to 3400·5) | 77·6* (69·9 to 86·1) | 52·3* (45·8 to 59·6) | 342·1 (246·2 to 455·9) | 79·4* (68·1 to 90·9) | 49·7* (40·1 to 59·0) |
| Sickle cell trait | 261 740·7 (249 515·4 to 272 735·9) | 57·0* (54·2 to 59·7) | 19·3* (17·1 to 21·3) | 1396·6 (929·4 to 2004·9) | 39·0* (32·0 to 49·0) | 13·8* (8·0 to 23·6) |
| Glucose-6-phosphate dehydrogenase deficiency | 337 628·8 (329 360·6 to 345 753·7) | 47·1* (42·1 to 51·9) | 11·4* (7·6 to 15·1) | 36·3 (24·8 to 50·4) | 40·5* (31·7 to 49·5) | 11·4* (4·8 to 18·1) |
| Glucose-6-phosphate dehydrogenase deficiency trait | 1 181 972·5 (1 174 352·1 to 1 188 844·0) | 38·6* (37·6 to 39·9) | 3·0* (2·2 to 3·9) | 48·8 (30·1 to 73·3) | 23·6 (−1·0 to 50·9) | −0·7 (−20·6 to 20·4) |
| Other haemoglobinopathies and haemolytic anaemias | 56 010·1 (54 470·2 to 57 258·6) | −2·3 (−5·5 to 1·3) | −26·6* (−29·0 to −24·0) | 1416·5 (936·5 to 2051·7) | −12·7* (−17·5 to −6·4) | −31·4* (−35·1 to −26·4) |
| Endocrine, metabolic, blood, and immune disorders | 79 556·0 (77 363·2 to 81 282·3) | 10·3* (6·9 to 13·8) | −16·2* (−18·8 to −13·7) | 2610·6 (1797·9 to 3629·0) | 6·9* (2·2 to 12·8) | −16·7* (−20·2 to −12·3) |
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| Musculoskeletal disorders | .. | .. | .. | 146 231·3 (103 763·1 to 194 304·6) | 60·7* (58·6 to 63·6) | 0·6 (−0·5 to 2·3) |
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| Rheumatoid arthritis | 16 863·2 (16 714·4 to 17 035·8) | 57·0* (54·7 to 59·1) | −5·1* (−6·5 to −3·8) | 3925·6 (2818·6 to 5178·5) | 56·8* (53·9 to 59·4) | −4·6* (−6·3 to −3·1) |
| Osteoarthritis | 241 825·0 (239 655·8 to 243 896·7) | 71·9* (69·8 to 74·3) | −2·6* (−3·8 to −1·2) | 12 811·1 (9030·0 to 17 281·2) | 75·4* (72·9 to 77·8) | −0·2 (−1·6 to 1·2) |
| Low back and neck pain | .. | .. | .. | 106 665·5 (74 116·9 to 142 959·7) | 55·8* (53·3 to 59·6) | −0·4 (−1·9 to 1·9) |
| Low back pain | 651 008·8 (641 143·4 to 662 885·1) | 56·8* (53·6 to 61·4) | −0·4 (−2·4 to 2·5) | 72 317·6 (49 051·0 to 99 738·5) | 56·7* (53·5 to 61·5) | 0·0 (−2·0 to 2·9) |
| Neck pain | 349 305·2 (341 160·3 to 359 767·4) | 54·1* (49·1 to 59·9) | −1·5 (−4·6 to 2·2) | 34 347·9 (23 792·0 to 47 418·5) | 54·0* (49·0 to 59·9) | −1·2 (−4·3 to 2·6) |
| Gout | 5825·6 (5750·0 to 5904·8) | 67·5* (64·6 to 70·8) | −2·3* (−4·0 to −0·3) | 185·5 (129·0 to 249·2) | 67·7* (62·6 to 73·3) | −1·8 (−4·7 to 1·4) |
| Other musculoskeletal disorders | 248 188·2 (216 691·1 to 281 933·6) | 78·4* (75·0 to 82·5) | 6·6* (5·0 to 8·9) | 22 643·6 (15 253·8 to 31 684·6) | 78·6* (75·0 to 82·9) | 7·0* (5·3 to 9·3) |
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| Other non-communicable diseases | .. | .. | .. | 117 951·0 (78 473·3 to 170 905·6) | 44·8* (42·8 to 46·7) | −4·1* (−5·4 to −3·0) |
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| Congenital anomalies | .. | .. | .. | 8022·5 (5922·6 to 10 168·4) | 61·4* (52·5 to 72·8) | 19·7* (13·2 to 28·2) |
| Neural tube defects | 1470·2 (1434·6 to 1508·2) | 59·2* (53·8 to 64·4) | 25·4* (21·2 to 29·6) | 461·2 (325·4 to 599·6) | 61·6* (53·7 to 70·7) | 27·9* (21·4 to 35·1) |
| Congenital heart anomalies | 34 315·9 (33 178·0 to 35 691·2) | 88·0* (80·3 to 98·5) | 40·0* (34·5 to 47·8) | 1230·4 (540·8 to 2079·5) | 86·8* (77·3 to 97·6) | 40·7* (34·5 to 48·5) |
| Orofacial clefts | 5807·6 (5621·9 to 5988·1) | 94·4* (86·1 to 105·9) | 47·9* (41·2 to 56·6) | 68·8 (45·6 to 98·8) | 76·3* (65·2 to 89·5) | 37·1* (28·4 to 47·3) |
| Down’s syndrome | 8538·5 (8185·7 to 8897·8) | 79·5* (70·1 to 88·2) | 32·8* (26·0 to 39·2) | 1167·1 (894·8 to 1459·7) | 91·3* (80·5 to 101·4) | 36·4* (29·3 to 42·9) |
| Turner’s syndrome | 257·5 (246·6 to 271·2) | 51·2* (42·6 to 62·3) | 14·8* (8·4 to 23·3) | 4·3 (2·2 to 6·9) | 52·1* (42·9 to 64·8) | 14·5* (7·5 to 23·8) |
| Klinefelter’s syndrome | 216·3 (207·1 to 226·7) | 42·0* (33·2 to 52·7) | 6·5* (0·0 to 14·5) | 1·3 (0·6 to 2·4) | 47·2* (37·0 to 58·8) | 5·5 (−1·8 to 13·9) |
| Chromosomal unbalanced rearrangements | 11 649·3 (11 154·1 to 12 235·1) | 74·0* (66·0 to 83·0) | 27·5* (21·7 to 34·0) | 1602·9 (1203·6 to 2038·4) | 85·1* (75·6 to 95·0) | 30·6* (24·8 to 37·1) |
| Other congenital anomalies | 25 840·0 (22 170·5 to 29 283·1) | 22·9* (17·2 to 28·7) | −10·6* (−14·7 to −6·5) | 3486·4 (2436·6 to 4641·2) | 38·7* (26·5 to 56·4) | 4·3 (−4·6 to 17·4) |
| Skin and subcutaneous diseases | .. | .. | .. | 39 051·0 (25 044·5 to 60 125·8) | 37·3* (33·8 to 40·3) | 0·3 (−2·0 to 2·3) |
| Dermatitis | 333 785·4 (289 927·3 to 381 312·4) | 38·7* (36·2 to 41·1) | −1·7* (−2·4 to −0·9) | 9278·4 (6029·0 to 13 326·7) | 36·8* (34·7 to 39·2) | −0·6 (−1·4 to 0·3) |
| Psoriasis | 58 264·1 (51 720·2 to 64 609·4) | 46·0* (44·0 to 48·8) | −2·2* (−3·0 to −1·6) | 4726·7 (3254·7 to 6621·9) | 45·9* (43·2 to 48·8) | −1·9* (−3·0 to −0·6) |
| Cellulitis | 1705·9 (1429·7 to 2040·3) | 19·1* (13·2 to 25·1) | −18·2* (−21·2 to −15·9) | 120·2 (78·6 to 170·2) | 18·6* (11·3 to 26·6) | −18·0* (−21·9 to −13·8) |
| Bacterial skin diseases | 5759·7 (4693·5 to 7278·2) | −6·7 (−16·2 to 3·7) | −23·8* (−29·9 to −17·6) | 32·6 (12·4 to 72·1) | −7·1 (−16·3 to 2·9) | −24·0* (−29·8 to −17·7) |
| Scabies | 66 107·5 (62 430·1 to 70 635·9) | 24·8* (15·0 to 40·1) | −4·0 (−11·3 to 7·3) | 1705·4 (967·2 to 2711·6) | 24·8* (14·8 to 40·3) | −3·7 (−11·2 to 7·8) |
| Fungal skin diseases | 683 713·8 (597 898·2 to 780 963·4) | 44·2* (41·2 to 47·9) | 3·0* (1·9 to 3·8) | 3847·2 (1574·5 to 8139·8) | 44·1* (41·1 to 47·9) | 3·3 (2·2 to 4·1) |
| Viral skin diseases | 127 923·6 (105 593·4 to 151 635·9) | 20·5* (17·9 to 24·3) | −1·8* (−3·1 to −0·3) | 3955·0 (2398·4 to 6150·9) | 20·4* (17·8 to 24·1) | −1·7 (−3·0 to 0·0) |
| Acne vulgaris | 661 634·9 (622 842·5 to 700 241·7) | 23·2* (13·9 to 32·6) | −0·4 (−7·8 to 7·3) | 7180·8 (3451·6 to 13 214·1) | 23·2* (13·7 to 32·7) | −0·3 (−7·7 to 7·4) |
| Alopecia areata | 8775·5 (8614·4 to 8937·9) | 46·1* (42·5 to 49·4) | −1·1 (−3·4 to 1·2) | 292·4 (186·8 to 435·2) | 45·6* (41·2 to 50·0) | −0·9 (−3·6 to 1·8) |
| Pruritus | 1024·6 (988·1 to 1074·1) | 55·3* (46·3 to 63·1) | −0·2 (−5·9 to 5·3) | 10·8 (5·1 to 20·0) | 54·8* (44·9 to 64·9) | 0·0 (−6·4 to 6·5) |
| Urticaria | 79 582·8 (72 812·3 to 86 296·3) | 60·5* (44·2 to 75·0) | 7·3 (−3·8 to 16·6) | 4720·7 (3036·5 to 6737·2) | 60·7* (43·4 to 75·5) | 7·7 (−3·5 to 17·6) |
| Decubitus ulcer | 1921·4 (1853·0 to 2001·2) | 59·5* (51·8 to 67·1) | −8·1* (−13·1 to −3·3) | 277·5 (196·0 to 371·2) | 58·1* (49·8 to 66·8) | −7·7* (−12·9 to −2·5) |
| Other skin and subcutaneous diseases | 495 327·6 (319 462·3 to 761 255·5) | 57·1* (48·5 to 64·4) | 0·0 (−0·9 to 0·9) | 2903·1 (1274·1 to 6123·6) | 57·0* (48·5 to 64·5) | 0·4 (−0·6 to 1·3) |
| Sense organ diseases | .. | .. | .. | 54 428·1 (36 458·4 to 76 075·4) | 47·4* (44·1 to 50·1) | −8·2* (−9·7 to −6·7) |
| Glaucoma | 10 899·9 (9853 2 to 12 002·8) | 63·0* (50·2 to 74·7) | −3·5 (−10·6 to 2·9) | 807·5 (571·6 to 1102·8) | 63·1* (54·8 to 70·9) | −4·6* (−9·7 to −0·2) |
| Cataract | 44 221·6 (39 326·0 to 48 603·1) | 47·5* (41·3 to 56·4) | −17·6* (−20·8 to −13·0) | 2916·7 (2055·1 to 3962·2) | 56·7* (50·6 to 63·9) | −12·5* (−15·7 to −8·6) |
| Macular degeneration | 13 873·8 (12 176·5 to 15 562·6) | 76·3* (69·4 to 89·3) | −1·6 (−5·6 to 5·1) | 725·6 (509·4 to 985·1) | 75·0* (69·0 to 87·8) | −4·4 (−8·6 to 1·4) |
| Uncorrected refractive error | 659 847·2 (648 298·7 to 671 446·7) | 52·0* (49·0 to 55·0) | −5·2* (−7·0 to −3·4) | 11 257·2 (7149·8 to 17 452·3) | 43·5* (40·4 to 47·2) | −8·9* (−10·6 to −7·0) |
| Age-related and other hearing loss | 1 128 939·1 (1 055 657·5 to 1 200 476·4) | 55·7* (52·7 to 58·4) | −6·5* (−7·9 to −5·2) | 32 579·7 (22 083·7 to 45 846·1) | 50·7* (45·4 to 54·8) | −7·9* (−10·2 to −5·4) |
| Other vision loss | 26 806·0 (24 116·0 to 29 696·9) | 19·9* (16·0 to 23·8) | −22·2* (−25·0 to −19·9) | 1793·5 (1260·4 to 2452·0) | 23·7* (19·4 to 27·6) | −21·1* (−23·5 to −19·0) |
| Other sense organ diseases | 164 612·2 (163 116·9 to 166 389·9) | 34·2* (32·5 to 36·2) | −0·2 (−1·4 to 1·2) | 4348·0 (2704·3 to 6435·1) | 33·7* (31·7 to 35·8) | 0·1 (−1·3 to 1·6) |
| Oral disorders | .. | .. | .. | 16 449·5 (10 022·3 to 25 506·3) | 47·6* (45·8 to 49·7) | −7·7* (−9·7 to −5·5) |
| Deciduous caries | 492 920·5 (490 657·1 to 495 385·2) | 4·4* (3·6 to 5·2) | −2·1* (−2·8 to −1·4) | 181·1 (79·0 to 350·9) | 5·7* (4·1 to 7·5) | −0·9 (−2·3 to 0·8) |
| Permanent caries | 2 633 328·8 (2 607 931·9 to 2 658 749·5) | 37·4* (35·8 to 39·6) | −1·2 (−2·3 to 0·4) | 2411·0 (1102·6 to 4664·5) | 40·5* (38·3 to 43·0) | 1·8* (0·1 to 3·7) |
| Periodontal diseases | 503 967·2 (496 870·4 to 511 448·4) | 66·7* (63·7 to 70·1) | 1·4 (−0·4 to 3·4) | 3286·0 (1318·3 to 6750·3) | 66·8* (63·8 to 70·3) | 1·7 (−0·2 to 3·7) |
| Edentulism and severe tooth loss | 250 683·6 (247 512·3 to 253 463·0) | 45·6* (43·4 to 47·9) | −16·4* (−17·7 to −15·1) | 6855·6 (4647·2 to 9420·4) | 45·6* (43·3 to 47·9) | −16·2* (−17·6 to −14·9) |
| Other oral disorders | 126 945·5 (125 452·3 to 128 568·2) | 44·7* (42·5 to 46·9) | −0·5 (−2·0 to 0·9) | 3715·7 (2347·5 to 5558·6) | 44·6* (42·2 to 46·9) | −0·3 (−1·9 to 1·2) |
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| Injuries | .. | .. | .. | 36 831·5 (26 895·7 to 48 748·0) | 0·3 (−13·7 to 11·3) | −37·0* (−45·4 to −30·0) |
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| Transport injuries | .. | .. | .. | 10 194·9 (7477·9 to 13 437·8) | 6·2 (−1·0 to 14·5) | −31·7* (−36·2 to −26·8) |
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| Road injuries | .. | .. | .. | 8593·4 (6305·9 to 11 313·7) | 6·9 (−0·7 to 15·8) | −31·0* (−35·8 to −25·8) |
| Pedestrian road injuries | 37 844·1 (37 457·1 to 38 216·7) | 53·7* (51·7 to 55·6) | 0·6 (−0·7 to 1·9) | 2271·8 (1657·1 to 2993·5) | 17·2* (8·9 to 27·0) | −23·6* (−28·5 to −17·8) |
| Cyclist road injuries | 13 678·6 (13 439·2 to 13 925·1) | 24·1* (22·1 to 26·2) | −14·9* (−16·3 to −13·4) | 812·4 (594·6 to 1074·2) | 2·8 (−3·5 to 9·9) | −33·9* (−37·9 to −29·5) |
| Motorcyclist road injuries | 32 483·6 (31 964·6 to 33 019·7) | 28·0* (25·5 to 30·0) | −17·2* (−18·9 to −15·9) | 1649·2 (1201·7 to 2204·5) | −4·2 (−12·2 to 5·1) | −38·2* (−43·1 to −32·5) |
| Motor vehicle road injuries | 60 733·7 (59 848·5 to 61 593·1) | 40·8* (39·3 to 42·4) | −2·7* (−3·7 to −1·5) | 3777·8 (2811·0 to 4946·9) | 8·1* (0·3 to 16·7) | −30·9* (−35·6 to −25·8) |
| Other road injuries | 1371·5 (1351·1 to 1393·6) | 17·9* (15·9 to 19·8) | −22·8* (−24·2 to −21·5) | 82·3 (61·0 to 107·3) | −5·7 (−11·4 to 1·0) | −40·1* (−43·4 to −36·1) |
| Other transport injuries | 26 293·0 (25 899·6 to 26 709·0) | 22·9* (20·3 to 25·2) | −21·7* (−23·5 to −20·1) | 1601·5 (1173·2 to 2118·5) | 2·2 (−3·1 to 8·5) | −35·1* (−38·5 to −31·2) |
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| Unintentional injuries | .. | .. | .. | 21 649·4 (16 036·0 to 28 726·9) | 17·9* (10·5 to 25·8) | −28·0* (−32·8 to −22·7) |
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| Falls | 250 044·4 (247 438·2 to 252 548·9) | 61·3* (59·7 to 62·8) | 0·9 (−0·2 to 1·8) | 12 818·1 (9356·9 to 16 996·8) | 23·5* (13·6 to 35·0) | −28·3* (−34·5 to −21·1) |
| Drowning | 6149·1 (6022·3 to 6275·4) | 13·7* (10·6 to 16·7) | −23·9* (−25·9 to −21·9) | 373·6 (273·4 to 485·1) | −8·6* (−13·5 to −2·4) | −37·9* (−40·9 to −34·1) |
| Fire, heat, and hot substances | 35 326·2 (34 097·3 to 36 575·8) | 7·4* (3·4 to 11·8) | −28·7* (−31·4 to −25·5) | 1172·2 (867·1 to 1551·4) | −4·7 (−10·0 to 0·6) | −36·8* (−39·8 to −33·8) |
| Poisonings | 925·2 (910·3 to 939·5) | 5·1* (2·8 to 7·0) | −29·2* (−30·7 to −27·9) | 78·7 (56·2 to 104·5) | −6·3* (−9·8 to −2·7) | −36·7* (−39·0 to −34·4) |
| Exposure to mechanical forces | .. | .. | .. | 3758·0 (2748·6 to 4985·4) | 5·2* (0·3 to 10·4) | −30·1* (−33·0 to −26·9) |
| Unintentional firearm injuries | 3729·0 (3639·3 to 3820·9) | 29·9* (26·7 to 33·3) | −13·3* (−15·4 to −11·1) | 146·6 (109·0 to 194·3) | 6·4 (−0·3 to 14·2) | −29·8* (−34·0 to −25·1) |
| Unintentional suffocation | 949·6 (923·4 to 979·8) | 66·5* (63·2 to 69·4) | 13·4* (11·6 to 15·0) | 54·2 (40·2 to 71·6) | 42·2* (34·7 to 50·1) | −3·3 (−8·1 to 1·6) |
| Other exposure to mechanical forces | 113 111·5 (105 859·7 to 120 514·4) | 15·7* (12·9 to 18·0) | −18·0* (−19·7 to −16·5) | 3557·2 (2597·7 to 4726·4) | 4·7 (0·0 to 9·8) | −30·4* (−33·3 to −27·3) |
| Adverse effects of medical treatment | 1526·1 (1226·7 to 1820·2) | 46·2* (44·0 to 48·5) | −1·0 (−2·4 to 0·4) | 201·0 (127·1 to 295·2) | 48·4* (46·1 to 50·7) | −5·7* (−7·2 to −4·0) |
| Animal contact | .. | .. | .. | 403·5 (299·5 to 527·6) | −6·3* (−10·6 to −1·4) | −36·4* (−39·0 to −33·5) |
| Venomous | 2274·1 (2204·9 to 2346·6) | 2·6 (−2·1 to 6·8) | −31·1* (−34·2 to −28·3) | 153·1 (110·5 to 201·1) | −7·5* (−12·6 to −2·2) | −37·1* (−40·5 to −33·6) |
| Non-venomous | 12 089·8 (10 522·9 to 13 775·5) | −5·6 (−10·9 to 0·0) | −32·8* (−35·9 to −29·6) | 250·5 (183·9 to 337·8) | −5·4 (−10·9 to 0·6) | −36·0* (−38·9 to −32·8) |
| Foreign body | .. | .. | .. | 254·8 (186·8 to 325·0) | 22·1* (16·2 to 29·0) | −19·4* (−23·3 to −15·0) |
| Pulmonary aspiration and foreign body in airway | 887·8 (873·4 to 902·7) | 42·5* (39·7 to 45·5) | −4·6* (−6·3 to −2·8) | 50·2 (38·4 to 64·6) | −2·7 (−10·5 to 7·4) | −33·7* (−38·6 to −27·2) |
| Foreign body in eyes | 1164·8 (737·5 to 1586·1) | 41·5* (37·7 to 46·7) | 0·4 (−1·5 to 2·3) | 60·3 (35·0 to 91·7) | 30·6* (26·0 to 34·9) | −10·4* (−15·4 to −6·9) |
| Foreign body in other body part | 3912·3 (3465·6 to 4383·6) | 42·0* (34·0 to 49·6) | −4·0* (−8·3 to −0·2) | 144·3 (108·0 to 186·5) | 30·1* (23·9 to 36·9) | −16·5* (−20·1 to −12·7) |
| Other unintentional injuries | 51 132·0 (49 359·0 to 52 946·0) | 45·2* (43·1 to 47·7) | −3·9* (−5·2 to −2·5) | 2589·5 (1905·1 to 3445·3) | 34·2* (29·7 to 39·1) | −16·0* (−18·5 to −13·3) |
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| Self-harm and interpersonal violence | .. | .. | .. | 1053·5 (778·0 to 1388·0) | 1·8 (−5·0 to 10·5) | −34·4* (−38·5 to −29·2) |
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| Self-harm | 5940·8 (5845·2 to 6051·2) | 21·5* (18·5 to 24·2) | −24·7* (−26·3 to −23·2) | 231·6 (167·0 to 307·3) | −1·7 (−6·9 to 5·4) | −39·0* (−42·2 to −34·8) |
| Interpersonal violence | .. | .. | .. | 821·9 (610·4 to 1077·7) | 2·8 (−4·5 to 12·0) | −33·0* (−37·4 to −27·3) |
| Assault with firearm | 3870·2 (3765·2 to 3974·2) | 46·7* (42·6 to 50·5) | −3·2* (−5·9 to −0·7) | 163·1 (120·0 to 216·6) | 21·9* (14·8 to 29·8) | −21·1* (−25·4 to −16·5) |
| Assault with sharp object | 6078·6 (5868·9 to 6311·1) | 41·9* (36·4 to 47·2) | −7·0* (−10·3 to −3·7) | 172·3 (124·9 to 233·2) | 18·5* (10·8 to 28·0) | −22·9* (−27·6 to −17·2) |
| Assault by other means | 10 133·4 (9835·8 to 10 448·3) | 21·4* (18·8 to 23·7) | −17·9* (−19·3 to −16·6) | 486·5 (364·2 to 635·7) | −6·4 (−12·9 to 2·4) | −38·8* (−42·9 to −33·4) |
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| Forces of nature, war, and legal intervention | .. | .. | .. | 3933·7 (1860·7 to 7821·0) | −50·7* (−57·7 to −40·2) | −67·9* (−72·6 to −61·0) |
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| Exposure to forces of nature | 14 335·5 (7133·3 to 28 680·1) | 8·2 (−4·6 to 29·0) | −37·4* (−45·6 to −24·5) | 556·8 (280·6 to 1117·0) | −0·7 (−15·1 to 22·3) | −36·7* (−45·8 to −22·0) |
| Collective violence and legal intervention | 43 478·1 (23 580·2 to 77 304·6) | −27·0* (−32·2 to −17·3) | −46·7* (−51·2 to −40·8) | 3376·9 (1547·3 to 6784·6) | −54·6* (−60·2 to −46·1) | −70·3* (−74·2 to −64·5) |
All data are reported with 95% uncertainty intervals. YLDs=years lived with disability.
*
Significant percentage change.