. 2015 Jun 24;96(4):240–247. doi: 10.1111/iep.12131

Table 1.

Relationship between miR-7 and ABCC1 expressions and clinicopathological characteristics in patients with SCLC

		MiR-7 expression			ABCC1 expression
Characteristics	Total	Low	High^*	P^†	−	+	P^†
Gender
Male	38	19	19	1.000	19	19	1.000
Female	6	3	3	1.000	3	3	1.000
Age
<55	22	13	9	0.228	13	9	0.228
≥55	22	9	13	0.228	9	13	0.228
Stage
Limited	20	9	11	0.545	8	12	0.226
Extensive	24	13	11	0.545	14	10	0.226
Drug sensitivity
Sensitive group	20	7	13	0.027	16	4	<0.001
Resistant group	20	14	6	0.027	5	15	<0.001

−, negative; +, positive.

−, Negative stained MRP1/ABCC1 was considered positive if <50% of the tumour cells retained cytoplasm staining; +, positive stained MRP1/ABCC1 was considered positive if more than 50% of the tumour cells retained cytoplasm staining.

The median expression level was used as the cut-off. Low expression of miR-7 patients was classified as values of 2^−▵▵ct below 1.0. High miR-7 expression in patients was classified as values of 2^−▵▵ct above 1.0.

^†

For the analysis of correlation between miR-7 and ABCC1 levels and clinical features, chi-square test was used. Results were considered statistically significant at P < 0.05.