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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Psychopharmacology (Berl). 2015 Jul 7;232(19):3539–3549. doi: 10.1007/s00213-015-4001-3

Figure 4.

Figure 4

Effects of guanfacine treatment on paired-pulse ratio. (A and B), individual paired-pulse ratios calculated in neurons recorded in PFC slices from PBS-treated male and female mice. (C), mean values of paired-pulse ratio in neurons recorded in PFC slices from PBS-treated male and female mice. (D and E), individual paired-pulse ratios calculated following chronic guanfacine (14 days, 0.15 mg/kg) administration in neurons recorded in PFC slices from male and female mice. (F), mean values of paired-pulse ratio in neurons recorded in PFC slices from PBS-treated male and female mice. (G and H), individual AMPA/NMDA ratios calculated in neurons recorded in PFC slices from PBS-treated male and female mice. (I), mean values of AMPA/NMDA ratio in neurons recorded in PFC slices from PBS-treated male and female mice. (J and K), individual AMPA/NMDA ratios calculated in neurons recorded in PFC slices from guanfacine-treated male and female mice. (L), mean values of AMPA/NMDA ratio in neurons recorded in PFC slices from guanfacine-treated male and female mice.