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. 2015 Jul 7;4(7):e246. doi: 10.1038/mtna.2015.18

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Copyright © 2015 American Society of Gene & Cell Therapy

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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8-mer LNAs stably sequester miR-372 in AGS xenografts and derepress LATS2. (a) Nondenaturing northern blot analysis of miR-372 (A,B) and miR-21 (C,D) in AGS-PM372 tumors treated with TLCo or an equimolar TL372+TL373 mix at 5 nanomoles/mouse (A,C) or with increasing doses (B,D). (b) Representative images of LATS2 immunostaining in AGS -PM372 tumors treated with either TLCo or TL372+373 at 5 nanomoles/mouse. Scale bars, 25 μm.