FIG 5.

Direct comparison of pressure inactivation of six human RVs derived from four serotypes. RV stock (10⁶ PFU/ml) in cell culture medium (MEM) was processed under pressures ranging from 200 MPa to 450 MPa held for 2 min at 4°C. The surviving viruses were determined by plaque assay. Data are the means of three replicates. Error bars represent standard deviations. Strain Wa was significantly (P < 0.05) more resistant to HPP inactivation than strains Ku and K8. Strain S2 was more significantly (P < 0.05) inactivated by HPP than the G1 strains (Wa, Ku, and K8). YO had significantly (P < 0.05) increased inactivation by HPP compared to the G2 and G1 strains. ST3 was the most sensitive strain (P < 0.05).