FIG 5.

Detection of gastrin-expressing cells in human nongastrinoma pancreatic endocrine tumors. (A) Number of tumors with gastrin expression among the three cohorts with pNETs analyzed. (B) Representative IHC stainings from two cohorts of human pancreatic endocrine tumors (MEN1 or sporadic). (C) IF stainings for the indicated factors in pancreatic endocrine tumors containing gastrin-immunoreactive cells. Arrows, gastrin-expressing cells coexpressing glucagon (top) or insulin (bottom). NF, nonfunctioning. Bars = 20 μm.