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Linoleic acid–derived oxylipins. 9-HODE and 13-HODE are also produced via the COX pathway (27, 61). COX, cyclooxygenase; CYP, cytochrome P450; DiHOME, dihydroxy-octadecenoic acid; EpOME, epoxy-octadecenoic acid; HODE, hydroxy-octadecadienoic acid; HpODE, hydroperoxy-octadecadienoic acid; LOX, lipoxygenase; oxo-ODE, oxo-octadecadienoic acid; TriHOME, trihydroxy-octadecenoic acid.
