Table 2.
The top ten best protective association models of 2-SNP combinations.
| Specific 2-SNP combination∗1 | Genotypes∗1 | Case number /control number |
OR | 95% CI | P value | Power |
|---|---|---|---|---|---|---|
| 1-2 | Others | 330/261 | 1 | 0.005∗2 | 0.792 | |
| 1-1 | 15/29 | 0.409 | 0.215–0.779 | |||
|
| ||||||
| 2-4 | Others | 330/261 | 1 | 0.010∗2 | 0.752 | |
| 1-1 | 15/28 | 0.424 | 0.222–0.810 | |||
|
| ||||||
| 1-3 | Others | 278/219 | 1 | 0.123 | 0.339 | |
| 1-2 | 67/71 | 0.743 | 0.509–1.085 | |||
|
| ||||||
| 2-3 | Others | 327/261 | 1 | 0.022∗2 | 0.629 | |
| 1-2 | 18/29 | 0.495 | 0.269–0.912 | |||
|
| ||||||
| 1-4 | Others | 310/247 | 1 | 0.073 | 0.432 | |
| 1-1 | 35/43 | 0.649 | 0.403–1.044 | |||
|
| ||||||
| 3-4 | Others | 310/247 | 1 | 0.073 | 0.432 | |
| 2-1 | 35/43 | 0.649 | 0.403–1.044 | |||
|
| ||||||
| 4-5 | Others | 311/249 | 1 | 0.096 | 0.385 | |
| 1-2 | 34/41 | 0.664 | 0.409–1.078 | |||
|
| ||||||
| 2-5 | Others | 325/261 | 1 | 0.048∗2 | 0.506 | |
| 1-2 | 20/29 | 0.554 | 0.306–1.002 | |||
|
| ||||||
| 1-5 | Others | 289/234 | 1 | 0.311 | 0.174 | |
| 1-2 | 56/56 | 0.810 | 0.538–1.218 | |||
|
| ||||||
| 2-3 | Others | 292/239 | 1 | 0.451 | 0.118 | |
| 2-1 | 53/51 | 0.851 | 0.558–1.296 | |||
∗1The information of the SNP and genotypes is provided in Table 1.
∗2The models have significance on the occurrence of breast cancer (P < 0.05).
OR = odds ratio.