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. 2015 Sep 8;5:13883. doi: 10.1038/srep13883

Figure 1. Circulating Gag-specific and SEB-induced CD4+ T cells secreting IL-22 in EU subjects.

Figure 1

PBMCs from healthy controls (HC, n = 15), EUs (n = 16) and HIV-infected individuals (n = 15) were cultivated with medium (baseline), HIV Gag peptide pools [Gag1 (p17), Gag2 (p24), and Gag3 (p15)], or SEB for 6 h and Brefeldin A for 4 h. CD4+ T cells secreting IL-17a (A) and IL-22 (B) were assessed using flow cytometry. Frequency of CD4+ T cells was subtracted from baseline. The results are expressed as medians and IQRs. *p ≤ 0.05 and **p ≤ 0.01, adjusted for multiple comparisons.