Table 1.
Sociodemographic and Behavioral Characteristics of Women with Negative Serologic Testing for HSV-2 at Enrollment, According to Study-Group Assignment.*
Variable | Tenofovir Gel (N = 205) |
Placebo Gel (N = 224) |
---|---|---|
Sociodemographic characteristic | ||
Age — yr | 22.2±3.6 | 21.6±3.4 |
Parity | 0.7±1.0 | 0.7±0.8 |
High-school education or more — no. (%) | 92 (44.9) | 98 (43.8) |
Income per month <1000 rands — no./total no. (%)† | 167/179 (93.3) | 173/185 (93.5) |
Using hormonal contraception — no. (%) | 202 (98.5) | 224 (100) |
Stable partner — no. (%)‡ | 202 (98.5) | 222 (99.1) |
Living with regular partner — no. (%)§ | 18 (8.8) | 9 (4.0) |
Sexual behavior | ||
Age at first sexual experience — yr | 17.5±2.1 | 17.4±1.8 |
Age of oldest partner in past 30 days — yr | 25.2±4.3 | 24.8±4.2 |
No. of lifetime sex partners | 2.2±2.1 | 3.0±12.1 |
No. of sex acts in past 30 days | 8.5±8.2 | 7.5±6.8 |
New sex partner in past 30 days — no. (%) | 1 (0.5) | 3 (1.3) |
Knows sex partner had other sex partners in past 30 days — no. (%) | 35 (17.1) | 41 (18.3) |
Knows sex partner had HIV test in past 30 days — no. (%) | 3 (1.5) | 7 (3.1) |
Reports alcohol consumption by partner and self before sex in general — no. (%) |
7 (3.4) | 7 (3.1) |
Reports alcohol consumption by partner or self before the last time they had sex — no. (%) |
51 (24.9) | 59 (26.3) |
Reports always using condom during sex — no. (%) | 61 (29.8) | 63 (28.1) |
Location of study site — no. of participants (%) | ||
Urban | 57 (27.8) | 57 (25.4) |
Rural | 148 (72.2) | 167 (74.6) |
Plus–minus values are means ±SD. There were no significant differences between the two groups, except for the difference in mean parity (P = 0.01) and in living with a regular partner (P = 0.03). HIV denotes human immunodefiency virus, and HSV-2 herpes simplex virus type 2.
A value of 1000 South African rands is equal to approximately 80 U.S. dollars.
A stable partner was defined as someone with whom the woman has a regular sexual relationship.
A regular partner included a husband or a stable partner.