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. Author manuscript; available in PMC: 2015 Sep 8.
Published in final edited form as: Gene Ther. 2009 Mar 12;16(5):689–699. doi: 10.1038/gt.2009.29

Figure 5.

Figure 5

Only T cells loaded at a low MOI and mDC are able to traffic to TDLN for delivery of reovirus in reovirus-immune mice. Mice (three per group) were immunized with 108 p.f.u. reovirus i.p. 2 weeks later the mice were seeded s.c. with 2 × 105 B16tk cells. After a further 10 days, the mice were treated with PBS, 2 × 107 p.f.u. reovirus or 2 × 106 T cells, iDC or mDC from GFP-transgenic mice loaded at MOI of 0 or 0.1 or 10. 3 days later the TDLN were explanted and dissociated. The presence of adoptively transferred cells was assessed by PCR screening for the presence of the GFP and Tyr-P (control) genes.