Table 2.
Odd ratios (ORs) of the myopathy risk associated with taking D1: Top 10 findings for Ntake ≥ MinSup, where Ntake is the number of events where the drug was committed during the event window
| D1 | OR | LCI | UCI | Ntake | Ranking | |
|---|---|---|---|---|---|---|
| MinSup = 200 | MinSup = 1,000 | |||||
| Tizanidine | 23.38 | 22.37 | 24.44 | 9,345 | 1 | 1 |
| Fentanyl | 19.69 | 18.33 | 21.15 | 3,738 | 2 | 2 |
| Methadone | 15.32 | 14.11 | 16.63 | 3,207 | 3 | 3 |
| Morphine | 13.51 | 12.38 | 14.75 | 3,005 | 4 | 4 |
| Tegaserod | 11.60 | 10.34 | 13.01 | 1,911 | 5 | 5 |
| Hydroxychloroquine | 11.28 | 10.59 | 12.02 | 6,466 | 6 | 6 |
| Cyclobenzaprine | 11.16 | 8.22 | 15.17 | 274 | 7 | |
| Naloxone | 10.69 | 8.67 | 13.17 | 608 | 8 | |
| Transdermal-Patch | 10.38 | 9.79 | 11.01 | 7,969 | 9 | 7 |
| Quinine | 10.36 | 8.35 | 12.87 | 577 | 10 | |
| Chlorzoxazone | 9.78 | 8.60 | 11.12 | 1,702 | 8 | |
| Tramadol | 9.25 | 8.97 | 9.54 | 32,327 | 9 | |
| Orphenadrine | 9.18 | 7.97 | 10.58 | 1,465 | 10 | |
Drugs reported for myopathy in SIDER 2 are shown in bold. LCI and UCI indicate the lower and upper limits of the confidence interval, respectively.