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. 2015 Sep 8;5:13631. doi: 10.1038/srep13631

Table 3. Solvation free energy change upon mutation at IT-state.

  ΔΔGsolv (kcal/mol)a
D76N +99.0 ± 26.2
D59P +135.8 ± 9.9
W60C −32.0 ± 13.1

aDifference in the solvation free energy, ΔΔGsolv = ΔGsolv(mutant) − ΔGsolv(wild type), from the wild type ± standard error.