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. 2015 Aug 25;2015:280238. doi: 10.1155/2015/280238

Figure 1.

Figure 1

Effects of adsorption of PIC (TLR3) or LPS (TLR4) agonists onto OVA/alum sensitization on OVA-induced cellular and humoral responses. (a) Protocol: C57BL/6 WT mice sensitized with s.c. OVA/alum in the presence or not of PIC (10 μg) or LPS (10 μg) on days 0 and 7 and challenged with OVA i.n. on days 14 and 21. Samples obtained on day 22. (b) Total number of cells and (c) eosinophils in BAL; ((d), (e), and (f)) levels of IL-5, IL-13, and IFN- g in BAL. ((g), (h), and (i)) Levels of serum isotypes: total IgE, OVA-specific IgG1, and OVA-specific IgG2a. Data shown as mean ± SE, one-way ANOVA: # P < 0.05 different from OVA/alum/PBS group (n = 5), and experiment was repeated twice.