Table 4. aEEG, HUS, and MRI examination and poor outcome at 18 months in preterm infants.
Poor outcome | CP | Hypophrenia | Audio-visual disorder | Death | |
---|---|---|---|---|---|
aEEG | |||||
Normal (n = 9) | 0 | 0 | 0 | 0 | 0 |
Mildly abnormal (n = 67) | 6 | 2 | 4 | 1 | 2 |
Severely abnormal (n = 63) | 18 | 10 | 14 | 1 | 3 |
P-value | 0.005 | 0.018 | 0.009 | 0.928 | 0.721 |
HUS | |||||
Normal (n = 46) | 1 | 1 | 1 | 0 | 0 |
Mildly abnormal (n = 144) | 15 | 1 | 8 | 5 | 3 |
Severely abnormal (n = 118) | 30 | 14 | 16 | 1 | 12 |
P-value | 0.013 | 0.000 | 0.008 | 0.203 | 0.003 |
MRI | |||||
Normal (n = 148) | 11 | 2 | 10 | 1 | 0 |
Mildly abnormal (n = 32) | 5 | 3 | 4 | 1 | 0 |
Severely abnormal (n = 30) | 13 | 11 | 10 | 3 | 3 |
P-value | 0.000 | 0.000 | 0.000 | 0.005 | 0.000 |
CP: cerebral palsy, aEEG: amplitude-integrated electroencephalography, HUS: head ultrasound, MRI: cranial magnetic resonance imaging. Hypophrenia: MDI < 70 according to Bayley Scales. Death: patients died from brain damage. Poor outcome: patients died from brain damage or survived with one or more of CP, hypophrenia, or audio-visual disorder. P-value: assessed the association between classifications of aEEG/HUS/MRI with poor outcomes using chi-square test, and P < 0.05 was considered significant.