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. 2015 Sep 8;7(1):93. doi: 10.1186/s13148-015-0126-9

Table 1.

Clinical characteristics of subjects

Never-obese Obesea P b
n 14 15
Age (years) 45 ± 11 46 ± 11 0.93
Weight (kg) 69 ± 7 115 ± 11 3.4 × 10−13
BMI (kg/m2) 25.2 ± 2.5 41.4 ± 4.5 4.1 × 10−12
Waist to hip ratio 0.85 ± 0.06 0.98 ± 0.06 5.0 × 10−6
Systolic blood pressure (mmHg) 123 ± 19 138 ± 22 0.073
Diastolic blood pressure (mmHg) 74 ± 6 85 ± 9 6.0 × 10−4
P-Glucose (mmol/l) 5.1 ± 0.4 5.7 ± 1.2 0.053
P-Insulin (mU/l) 4.6 ± 2.3 16.0 ± 10.3 3.7 × 10−4
P-Cholesterol (mmol/l) 4.7 ± 1.0 4.9 ± 0.7 0.57
P-HDL Cholesterol (mmol/l) 1.5 ± 0.4 1.1 ± 0.3 0.0058
P-Triglycerides (mmol/l) 0.86 ± 0.72 1.67 ± 0.92 0.013
P-NEFA (mmol/l) 0.57 ± 0.17 0.83 ± 0.16 2.4 × 10−4
P-Apolipoprotein B (g/l) 0.83 ± 0.25 0.96 ± 0.25 0.19
P-Apolipoprotein A1 (g/l) 1.39 ± 0.22 1.19 ± 0.24 0.028
Mean fat cell volume (pl) 443 ± 169 994 ± 184 5.5 × 10−9

aThree of the obese women had type 2 diabetes, of which two were treated with diet plus metformin, and one woman with diet alone. Nine were treated for hypertension and one patient had stable multiple sclerosis and did not receive any drugs

bComparison of control and obese group with unpaired t test. Values are mean ± SD