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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Drug Test Anal. 2015 Sep 1;8(8):779–791. doi: 10.1002/dta.1856

Figure 3. Combined extracted chromatograms of AH-7921 and its metabolites after hepatocyte incubation.

Figure 3

A) Combined extracted ion chromatograms of all metabolites (M1 to M12) after 1 (dashed line) and 3 h (continuous line) of incubation in 1 + 4 diluted samples

B) Extracted ion chromatogram for m/z 345.1131 ± 0.005 corresponding to AH-7921 metabolites generated by hydroxylation

C) Extracted ion chromatogram for m/z 331.0975 ± 0.005 corresponding to AH-7921 metabolites generated by demethylation and hydroxylation

D) Extracted ion chromatogram for m/z 317.0818 ± 0.005 corresponding to AH-7921 metabolites generated by di-demethylation and hydroxylation