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. 2011 May 4;31(18):6928–6938. doi: 10.1523/JNEUROSCI.6271-10.2011

Figure 7.

Figure 7.

AMPA receptors from stargazer cerebellar Purkinje neurons resemble two-TARP γ-7-containing recombinant AMPA receptors. A–D, Representative traces of glutamate-evoked, kainate-evoked, and CTZ-potentiated glutamate-evoked currents from wild-type (+/+) and stargazer (stg/stg) cerebellar Purkinje neurons. E, Glutamate-evoked currents from stargazer Purkinje neurons are reduced relative to wild-type Purkinje neurons. F, CTZ-potentiated glutamate-evoked currents from Purkinje neurons from both stargazer and wild-type mice are similar. G, Glutamate-evoked AMPA receptor currents from wild-type and stargazer cerebellar Purkinje neurons do not exhibit resensitization. H, Both wild-type and stargazer cerebellar Purkinje neurons receptors exhibit high IKA/IGlu. Note that these IKA/IGlu ratios are similar to those from two-TARP γ-7 and different from four-TARP γ-7 and from γ-7 plus CNIH-2 AMPA receptors (dotted lines) (Fig. 5). *p < 0.05 when compared with wild-type littermate controls.