TABLE 1:
Mean flea counts and percentage efficacy observed in cats treated with an oral tablet formulation of spinosad compared with placebo-treated controls 24 hours after dosing and 48 hours after each artificial infestation in laboratory dose confirmation studies
| Geometric and (arithmetic) mean flea counts and % efficacy* |
|||||||
|---|---|---|---|---|---|---|---|
| Study | Dose of spinosad (mg/kg) | Day: | 1 | 7 | 14 | 21 | 28 |
| 1. France | 50–75 | 0.0 (0.0) 100.0% |
0.0 (0.0) 100.0% |
0.3 (0.6) 99.7% |
0.4 (2.1) 99.5% |
1.5 (4.6) 98.1% |
|
| 2. Germany | 50–75 | 0.0 (0.0) 100.0% |
0.4 (0.6) 99.3% |
0.0 (0.0) 100.0% |
0.1 (0.1) 99.9% |
0.6 (0.9) 98.9% |
|
*% efficacy based on geometric means