Figure 2. APOL gene family in selected primate species and mouse.
Genes, lost genes, and pseudogenes are represented by plain black box, empty box, and light gray box with Ψ, respectively. The hashed boxes represent mouse homologous, but not orthologous, genes. (1) Macaque also exhibits an APOL2.1 gene and an APOL7 pseudogene.
(2) Baboon also exhibits two APOL2.1 pseudogenes and an APOL7 pseudogene. The trypanolytic potential against T. brucei is also depicted. [Permission pending from Capewell et al., Parasitology, 2015 - PMID:25656360]