Figure 1.
Cardiac function. Cardiac function was decreased in db/db mice and increased by Ang-(1–7) treatment as measured by echocardiography and thermodilution method. The measures of cardiac function included (A) cardiac output, (B) cardiac index, (C) dP/dTmin, (D) dP/dTmax and (E) fractional shortening. (Hz – heterozygous; db – diabetic). **Significantly reduced compared with heterozygous mice (P < 0.01). Significantly increased compared with db saline, †P < 0.05; ††P < 0.01, calculated using one-way anova.