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Evans blue (EB) extravasation in the lung of mice that received vehicle (veh, n = 5) or oleic acid (0.15 μL·g−1, n = 17) injected into the tail vein. The EP4 receptor agonist ONO AE1-329 (20 μg per mouse, n = 15) was given intranasally. Each point shows microgram EB per lung of one animal 90 min after oleic acid injection. Data were analysed by one-way anova and multiple comparisons were calculated with Tukey’s post test. *P < 0.05.
