Table 1.

OM concentration-dependent mechanical and kinetic effects in permeabilized cardiomyocytes and diaphragm muscle fibres

	Cardiomyocytes	Diaphragm muscle fibres with low ktr,max	Diaphragm muscle fibres with high ktr,max
EC50 for Ca2+ sensitization of force production	0.08 ± 0.01	0.16 ± 0.03	#
EC50 for Fpassive increase	0.26 ± 0.11	0.69 ± 0.11	No effect
EC50 for ktr decrease	#	0.29 ± 0.04	No effect

EC₅₀ values (in μM), determined at submaximal [Ca²⁺] (pCa 6.0 or pCa 5.8) for each muscle preparations are shown as means ± SEM.

^#EC₅₀ could not be determined.