Table 6. Data used for determining L2 composition.
| Controls | Heaves | p value | |
|---|---|---|---|
| Histology | |||
| N [airways/horse] | 4.67±0.57 | 5±2.16 | 0.58 |
| Pi [mm] | 18.94±1.91 | 20.09±3.93 | 1.00 |
| ECM thickness [mm] | 0.0833±0.014 | 0.1356±0.025 | 0.02 |
| ASM thickness [mm] | 0.0762±0.008 | 0.1254±0.04 | 0.057 |
| Submucosal thickness [mm] | 0.160±0.011 | 0.261±0.05 | 0.027 |
| Submucosal ECM % at histology | 52±3.2 | 53.5±2.9 | 0.3 |
| Submucosal ASM % at histology | 48±3.2 | 46.5±2.9 | 0.3 |
| EBUS | |||
| N [airways/horse] | 7.67±5303 | 8.5±3.70 | 0.85 |
| Pi [mm] | 16.19±1.71 | 19.86±1.61 | 0.11 |
| L1 thickness [mm] | 0.11±0.003 | 0.127±0.010 | 0.06 |
| L2 thickness [mm] | 0.177±0.022 | 0.269±0.021 | 0.004 |
| Submucosal thickness [mm] | 0.287±0.024 | 0.397±0.015 | 0.024 |
| Submucosal L1% at EBUS | 38.5±2.5 | 32.1±3.2 | 0.037 |
| Submucosal L2% at EBUS | 61.5±2.5 | 67.9±3.2 | 0.037 |
| Composition of L1 | |||
| ECM% | 100 | 100 | 1 |
| ASM% | 0 | 0 | 1 |
| Composition of L2 | |||
| ECM% | 22.1±8.9 | 28.1±5.7 | 0.63 |
| ASM% | 77.9±8.9 | 71.9±5.7 | 0.63 |
| Others | |||
| Shrinkage (%) | 44.28±4.88 | 47.41±7.92 | 0.7 |
Values are presented as mean±SD of the values obtained from the airways of 4 horses with heaves and 3 controls. Bold characters indicate significance as results of t-tests. Mean values per horse were used as statistical unit.