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. 2015 Aug 4;3(8):e12480. doi: 10.14814/phy2.12480

Figure 2.

Figure 2

Expression of epithelial sodium channels (ENaC) and Cl− channels (CFTR and ANO-1) in human nasal epithelial cells from patients harboring SLC26A4 mutations (DFNB4) and controls. (A) The mRNA expression patterns in the cells from patients with DFNB4 (n = 3) are similar to those in controls (n = 3), except for CFTR, which shows low levels of expression in the epithelia from DFNB4 patients. *indicates P < 0.05, compared to controls. (B) Amiloride-sensitive and ATP-induced short circuit current is similar in the cells from patients with DFNB4 (n = 4) to those in the controls (n = 3). Forskolin–induced current is smaller in the DNFB cells than those in the control cells.