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. 2015 Aug 19;3(8):e12501. doi: 10.14814/phy2.12501

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© 2015 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Regulation of gastric epithelial cell proliferation by gastrin in noggin TG-mice. Gastric paraffin sections from 12-week-old wild type (WT) (A), noggin TG (NogTG) (B), gastrin knock out (GasKO) (C), and NogTG;GasKO (D) mice were stained with antiproliferating cell nuclear antigen (PCNA) antibodies. Graph bars represent the number of PCNA-positive nuclei detected in the different groups of mice. Values are shown as means ± SE. *P < 0.05. Numbers in parenthesis indicate the number of separate mice that were used for the studies.