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Femoral arterial blood flow (A), leg O2 delivery (B), mean femoral arterial blood pressure (C), leg arteriovenous O2 difference (D), leg vascular conductance (E), and leg O2 uptake (F) in young and older subjects during knee-extensor exercise performed at 6 W, 12 W, and 40% Wmax (19 ± 1 and 15 ± 1 W: young and older) without (CON) and with sildenafil. Significant difference from CON within same condition: *P < 0.05.
