Table 1. Repeatability of thickness estimates and retinal layers in a mixed cohort of healthy controls and MS/CIS patients as measured by intraclass correlation coefficients (ICC) with 95%-confidence intervals.
Estimate | mRNFL | GCL | IPL | GCIP | INL | OPL | ONL |
---|---|---|---|---|---|---|---|
A | 0.98 [0.99–0.97] | 0.99 [0.99–0.98] | 0.99 [0.99–0.98] | 1.00 [1.00–1.00] | 0.97 [0.98–0.96] | 0.82 [0.88–0.72] | 0.98 [0.99–0.97] |
B | 0.97 [0.98–0.95] | 0.99 [1.00–0.99] | 0.99 [0.99–0.98] | 1.00 [1.00–1.00] | 0.96 [0.98–0.94] | 0.75 [0.84–0.63] | 0.97 [0.98–0.95] |
C | 0.98 [0.99–0.97] | 1.00 [1.00–0.99] | 0.99 [1.00–0.99] | 1.00 [1.00–1.00] | 0.98 [0.99–0.96] | 0.78 [0.86–0.68] | 1.00 [1.00–0.99] |
D | 0.98 [0.99–0.97] | 0.96 [0.98–0.94] | 0.96 [0.97–0.93] | 0.98 [0.99–0.97] | 0.87 [0.92–0.80] | 0.87 [0.92–0.80] | 1.00 [1.00–0.99] |
E | 0.97 [0.98–0.95] | 0.99 [1.00–0.99] | 0.98 [0.99–0.97] | 1.00 [1.00–0.99] | 0.90 [0.94–0.85] | 0.69 [0.80–0.56] | 0.99 [1.00–0.99] |
F | 0.88 [0.92–0.81] | 0.99 [0.99–0.99] | 0.98 [0.99–0.97] | 0.99 [1.00–0.99] | 0.83 [0.89–0.75] | 0.62 [0.75–0.47] | 0.92 [0.95–0.87] |
G | 0.96 [0.98–0.94] | 0.93 [0.95–0.88] | 0.89 [0.93–0.83] | 0.94 [0.96–0.91] | 0.72 [0.82–0.59] | 0.68 [0.79–0.54] | 0.99 [0.99–0.99] |
H | 0.92 [0.95–0.87] | 0.96 [0.98–0.94] | 0.96 [0.97–0.93] | 0.98 [0.99–0.97] | 0.73 [0.82–0.60] | 0.59 [0.72–0.43] | 0.98 [0.99–0.98] |
I | 0.81 [0.88–0.71] | 0.96 [0.97–0.93] | 0.93 [0.96–0.89] | 0.98 [0.99–0.97] | 0.83 [0.90–0.75] | 0.55 [0.69–0.38] | 0.98 [0.99–0.97] |
J | 0.92 [0.95–0.88] | 0.82 [0.89–0.73] | 0.77 [0.86–0.66] | 0.86 [0.91–0.79] | 0.76 [0.85–0.65] | 0.80 [0.87–0.70] | 0.92 [0.95–0.87] |
K | 0.98 [0.99–0.97] | NA | NA | 1.00 [1.00–1.00] | NA | NA | NA |
L | 0.99 [0.99–0.98] | NA | NA | 1.00 [1.00–1.00] | NA | NA | NA |
Abbreviations: mRNFL = macular retinal nerve fiber layer, GCL = ganglion cell layer, IPL = inner plexiform layer, GCIP = combined GCL and IPL, INL = inner nuclear layer, OPL = outer plexiform layer, ONL = outer nuclear layer.